Human Gene ST7L (uc009wgi.1)
  Description: Homo sapiens suppression of tumorigenicity 7 like (ST7L), transcript variant 4, mRNA.
RefSeq Summary (NM_138729): This gene was identified by its similarity to the ST7 tumor suppressor gene found in the chromosome 7q31 region. This gene is clustered in a tail-to-tail manner with the WNT2B gene in a chromosomal region known to be deleted and rearranged in a variety of cancers. Several transcript variants encoding many different isoforms have been described, but some have not been fully characterized. [provided by RefSeq, Feb 2011].
Transcript (Including UTRs)
   Position: hg19 chr1:113,084,573-113,161,761 Size: 77,189 Total Exon Count: 12 Strand: -


Page IndexSequence and LinksPrimersCTDRNA-Seq ExpressionMicroarray Expression
Other SpeciesmRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr1:113,084,573-113,161,761)mRNA (may differ from genome)No protein
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS
EnsemblExonPrimerGeneNetworkH-INVHGNCLynx
PubMed

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 11.15 RPKM in Testis
Total median expression: 109.42 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  BX538338 - Homo sapiens mRNA; cDNA DKFZp686O14208 (from clone DKFZp686O14208).
BC047392 - Homo sapiens suppression of tumorigenicity 7 like, mRNA (cDNA clone MGC:48464 IMAGE:5273549), complete cds.
BX537988 - Homo sapiens mRNA; cDNA DKFZp686N2430 (from clone DKFZp686N2430); complete cds.
AK095837 - Homo sapiens cDNA FLJ38518 fis, clone HCHON2000738, highly similar to Homo sapiens suppression of tumorigenicity 7 like (ST7L), transcript variant 3, mRNA.
AK021719 - Homo sapiens cDNA FLJ11657 fis, clone HEMBA1004573, weakly similar to Homo sapiens mRNA for HELG protein.
AK295955 - Homo sapiens cDNA FLJ60584 complete cds, highly similar to Homo sapiens suppression of tumorigenicity 7 like (ST7L), transcript variant 2, mRNA.
AK295507 - Homo sapiens cDNA FLJ60556 complete cds, highly similar to Homo sapiens suppression of tumorigenicity 7 like (ST7L), transcript variant 2, mRNA.
BC065501 - Homo sapiens suppression of tumorigenicity 7 like, mRNA (cDNA clone MGC:70568 IMAGE:4417786), complete cds.
AK097837 - Homo sapiens cDNA FLJ40518 fis, clone TESTI2046721, highly similar to Homo sapiens mRNA for HELG protein.
AB081317 - Homo sapiens ST7L mRNA for ST7L isoform 1, complete cds.
AK291042 - Homo sapiens cDNA FLJ76280 complete cds, highly similar to Homo sapiens suppression of tumorigenicity 7 like (ST7L), transcript variant 1, mRNA.
AB081318 - Homo sapiens ST7L mRNA for ST7L isoform 2, complete cds.
AB081319 - Homo sapiens ST7L mRNA for ST7L isoform 3, complete cds.
KJ894079 - Synthetic construct Homo sapiens clone ccsbBroadEn_03473 ST7L gene, encodes complete protein.
BC027898 - Homo sapiens cDNA clone IMAGE:5228023.
BX640667 - Homo sapiens mRNA; cDNA DKFZp686N05164 (from clone DKFZp686N05164); complete cds.
AK301869 - Homo sapiens cDNA FLJ55859 complete cds, highly similar to Homo sapiens suppression of tumorigenicity 7 like (ST7L), transcript variant 4, mRNA.
BC037830 - Homo sapiens suppression of tumorigenicity 7 like, mRNA (cDNA clone MGC:42217 IMAGE:4812133), complete cds.
AB081320 - Homo sapiens ST7L mRNA for ST7L isoform 4, complete cds.
EU831659 - Synthetic construct Homo sapiens clone HAIB:100066688; DKFZo007G1019 suppression of tumorigenicity 7 like protein (ST7L) gene, encodes complete protein.
EU831742 - Synthetic construct Homo sapiens clone HAIB:100066771; DKFZo003G1020 suppression of tumorigenicity 7 like protein (ST7L) gene, encodes complete protein.
AK308727 - Homo sapiens cDNA, FLJ98768.
AK304004 - Homo sapiens cDNA FLJ59279 complete cds, highly similar to Homo sapiens suppression of tumorigenicity 7 like (ST7L), transcript variant 2, mRNA.
AK000291 - Homo sapiens cDNA FLJ20284 fis, clone HEP04227.
AK225307 - Homo sapiens mRNA for suppression of tumorigenicity 7-like isoform 2 variant, clone: HEP04227.
CU688054 - Synthetic construct Homo sapiens gateway clone IMAGE:100021765 5' read ST7L mRNA.
DQ572500 - Homo sapiens piRNA piR-40612, complete sequence.
JD227376 - Sequence 208400 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: AK308727
UCSC ID: uc009wgi.1
RefSeq Accession: NM_138729

-  Gene Model Information
 
category: nearCoding nonsense-mediated-decay: no RNA accession: AK308727.1
exon count: 12CDS single in 3' UTR: no RNA size: 1395
ORF size: 0CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 226.00frame shift in genome: no % Coverage: 99.71
has start codon: no stop codon in genome: no # of Alignments: 1
has end codon: no retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.