Human Gene RDX (uc009yxx.1)
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Sequence and Links to Tools and Databases
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Primer design for this transcript
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Genetic Association Studies of Complex Diseases and Disorders
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MalaCards Disease Associations
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MalaCards Gene Search: RDX
Diseases sorted by gene-association score: deafness, autosomal recessive 24* (1246), nonsyndromic hearing loss and deafness* (283), autosomal recessive non-syndromic sensorineural deafness type dfnb* (117), dfnb24 nonsyndromic hearing loss and deafness* (100), nonsyndromic deafness* (81), neurofibromatosis, type 2 (21), kindler syndrome (9), meningioma, familial (6), pathologic nystagmus (5) * = Manually curated disease association
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Comparative Toxicogenomics Database (CTD)
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
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Microarray Expression Data
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Orthologous Genes in Other Species
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Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse | Rat | Zebrafish | D. melanogaster | C. elegans | S. cerevisiae |
No ortholog | No ortholog | No ortholog | No ortholog | No ortholog | No ortholog |
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Descriptions from all associated GenBank mRNAs
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DQ916741 - Homo sapiens radixin isoform e (RDX) mRNA, complete cds, alternatively spliced. DQ916742 - Homo sapiens radixin isoform f (RDX) mRNA, complete cds, alternatively spliced. DQ916738 - Homo sapiens radixin isoform b (RDX) mRNA, complete cds, alternatively spliced. DQ916739 - Homo sapiens radixin isoform c (RDX) mRNA, complete cds, alternatively spliced. DQ916740 - Homo sapiens radixin isoform d (RDX) mRNA, complete cds, alternatively spliced. AL137751 - Homo sapiens mRNA; cDNA DKFZp434I0812 (from clone DKFZp434I0812); partial cds. BX648536 - Homo sapiens mRNA; cDNA DKFZp779D2226 (from clone DKFZp779D2226). BC047109 - Homo sapiens radixin, mRNA (cDNA clone MGC:48283 IMAGE:5284438), complete cds. JD278683 - Sequence 259707 from Patent EP1572962. AK295075 - Homo sapiens cDNA FLJ58499 complete cds, highly similar to Radixin. L02320 - Human radixin mRNA, complete cds. AK316061 - Homo sapiens cDNA, FLJ78960 complete cds, highly similar to Radixin. AK312903 - Homo sapiens cDNA, FLJ93349, Homo sapiens radixin (RDX), mRNA. KJ897461 - Synthetic construct Homo sapiens clone ccsbBroadEn_06855 RDX gene, encodes complete protein. KR710945 - Synthetic construct Homo sapiens clone CCSBHm_00018338 RDX (RDX) mRNA, encodes complete protein. AB527544 - Synthetic construct DNA, clone: pF1KB6120, Homo sapiens RDX gene for radixin, without stop codon, in Flexi system. BC020751 - Homo sapiens radixin, mRNA (cDNA clone IMAGE:4691774), partial cds. BC002626 - Homo sapiens radixin, mRNA (cDNA clone IMAGE:3607251), partial cds.
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Biochemical and Signaling Pathways
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KEGG - Kyoto Encyclopedia of Genes and Genomes hsa04810 - Regulation of actin cytoskeleton
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Other Names for This Gene
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Alternate Gene Symbols: DQ916741, NM_001260493 UCSC ID: uc009yxx.1 RefSeq Accession: NM_001260493
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GeneReviews for This Gene
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GeneReviews article(s) related to gene RDX: deafness-overview (Genetic Hearing Loss Overview)
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Gene Model Information
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category:
| nearCoding
| nonsense-mediated-decay:
| yes
| RNA accession:
| DQ916741.1
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exon count:
| 17 | CDS single in 3' UTR:
| no
| RNA size:
| 2558 |
ORF size:
| 0 | CDS single in intron:
| no
| Alignment % ID:
| 99.96 |
txCdsPredict score:
| 3430.00 | frame shift in genome:
| no
| % Coverage:
| 100.00 |
has start codon:
| yes
| stop codon in genome:
| no
| # of Alignments:
| 1 |
has end codon:
| yes
| retained intron:
| no
| # AT/AC introns
| 0 |
selenocysteine:
| no
| end bleed into intron:
| 0 | # strange splices:
| 0 |
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Click here
for a detailed description of the fields of the table above.
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Methods, Credits, and Use Restrictions
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Click here
for details on how this gene model was made and data restrictions if any.
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