Description: Homo sapiens potassium channel tetramerisation domain containing 10 (KCTD10), mRNA. RefSeq Summary (NM_031954): The protein encoded by this gene binds proliferating cell nuclear antigen (PCNA) and may be involved in DNA synthesis and cell proliferation. In addition, the encoded protein may be a tumor suppressor. Several protein-coding and non-protein coding transcript variants have been found for this gene. [provided by RefSeq, Dec 2015]. Transcript (Including UTRs) Position: hg19 chr12:109,886,460-109,907,533 Size: 21,074 Total Exon Count: 6 Strand: - Coding Region Position: hg19 chr12:109,889,400-109,907,527 Size: 18,128 Coding Exon Count: 6
ID:F5GWA4_HUMAN DESCRIPTION: SubName: Full=BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3; SIMILARITY: Contains 1 BTB (POZ) domain. CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
Cholesterol, HDL Cristen J Willer et al. Nature genetics 2008, Newly identified loci that influence lipid concentrations and risk of coronary artery disease., Nature genetics.
[PubMed 18193043]
Cholesterol, HDL Sekar Kathiresan et al. Nature genetics 2009, Common variants at 30 loci contribute to polygenic dyslipidemia., Nature genetics.
[PubMed 19060906]
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on F5GWA4
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
