Description: Homo sapiens coiled-coil domain containing 122 (CCDC122), mRNA. RefSeq Summary (NM_144974): This gene encodes a protein that contains a coiled-coil domain. Naturally occurring mutations in this gene are associated with leprosy. [provided by RefSeq, Apr 2017]. Transcript (Including UTRs) Position: hg19 chr13:44,410,489-44,453,826 Size: 43,338 Total Exon Count: 7 Strand: - Coding Region Position: hg19 chr13:44,411,416-44,443,512 Size: 32,097 Coding Exon Count: 5
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Genetic Association Studies of Complex Diseases and Disorders
Genetic Association Database (archive): CCDC122 CDC HuGE Published Literature: CCDC122 Positive Disease Associations: Body Mass Index
, Leprosy Related Studies:
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
ModBase Predicted Comparative 3D Structure on Q5T0U0
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.