Human Gene KHNYN (uc010alw.3)
Description: Homo sapiens KH and NYN domain containing (KHNYN), mRNA.
RefSeq Summary (NM_015299): This gene encodes a protein containing a ribonuclease NYN domain. The function of this protein has yet to be determined. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014].
Transcript (Including UTRs)
Position: hg19 chr14:24,899,160-24,910,547 Size: 11,388 Total Exon Count: 8 Strand: +
Coding Region
Position: hg19 chr14:24,899,937-24,906,491 Size: 6,555 Coding Exon Count: 7
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: KHNYN_HUMAN
DESCRIPTION: RecName: Full=Protein KHNYN; AltName: Full=KH and NYN domain-containing protein;
SIMILARITY: Belongs to the N4BP1 family.SEQUENCE CAUTION: Sequence=BAA20781.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Primer design for this transcript
Genetic Association Studies of Complex Diseases and Disorders
Genetic Association Database (archive): KHNYN
CDC HuGE Published Literature: KHNYN
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR021869 - RNase_Zc3h12
Pfam Domains: PF11977 - Zc3h12a-like Ribonuclease NYN domain
ModBase Predicted Comparative 3D Structure on O15037
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse Rat Zebrafish D. melanogaster C. elegans S. cerevisiae
No ortholog No ortholog No ortholog No ortholog No ortholog No ortholog
Gene Details
Gene Sorter
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
AB002321 - Homo sapiens mRNA for KIAA0323 gene.AB383849 - Synthetic construct DNA, clone: pF1KSDA0323, Homo sapiens KIAA0323 gene for KIAA0323 protein, complete cds, without stop codon, in Flexi system.LF210095 - JP 2014500723-A/17598: Polycomb-Associated Non-Coding RNAs.AK291680 - Homo sapiens cDNA FLJ75063 complete cds.BX161465 - human full-length cDNA clone CS0DI064YL03 of Placenta of Homo sapiens (human).BC042554 - Homo sapiens KIAA0323, mRNA (cDNA clone MGC:35260 IMAGE:5173707), complete cds.KJ904685 - Synthetic construct Homo sapiens clone ccsbBroadEn_14079 KHNYN-like gene, encodes complete protein.BC015780 - Homo sapiens KIAA0323, mRNA (cDNA clone IMAGE:4856920), partial cds.MA445672 - JP 2018138019-A/17598: Polycomb-Associated Non-Coding RNAs.LF334580 - JP 2014500723-A/142083: Polycomb-Associated Non-Coding RNAs.LF334581 - JP 2014500723-A/142084: Polycomb-Associated Non-Coding RNAs.LF334582 - JP 2014500723-A/142085: Polycomb-Associated Non-Coding RNAs.LF334583 - JP 2014500723-A/142086: Polycomb-Associated Non-Coding RNAs.LF334584 - JP 2014500723-A/142087: Polycomb-Associated Non-Coding RNAs.LF334585 - JP 2014500723-A/142088: Polycomb-Associated Non-Coding RNAs.LF334586 - JP 2014500723-A/142089: Polycomb-Associated Non-Coding RNAs.MA570157 - JP 2018138019-A/142083: Polycomb-Associated Non-Coding RNAs.MA570158 - JP 2018138019-A/142084: Polycomb-Associated Non-Coding RNAs.MA570159 - JP 2018138019-A/142085: Polycomb-Associated Non-Coding RNAs.MA570160 - JP 2018138019-A/142086: Polycomb-Associated Non-Coding RNAs.MA570161 - JP 2018138019-A/142087: Polycomb-Associated Non-Coding RNAs.MA570162 - JP 2018138019-A/142088: Polycomb-Associated Non-Coding RNAs.MA570163 - JP 2018138019-A/142089: Polycomb-Associated Non-Coding RNAs.JD424043 - Sequence 405067 from Patent EP1572962.LF334589 - JP 2014500723-A/142092: Polycomb-Associated Non-Coding RNAs.JD348451 - Sequence 329475 from Patent EP1572962.JD557739 - Sequence 538763 from Patent EP1572962.JD455681 - Sequence 436705 from Patent EP1572962.LF334590 - JP 2014500723-A/142093: Polycomb-Associated Non-Coding RNAs.LF334591 - JP 2014500723-A/142094: Polycomb-Associated Non-Coding RNAs.JD360720 - Sequence 341744 from Patent EP1572962.LF334592 - JP 2014500723-A/142095: Polycomb-Associated Non-Coding RNAs.LF210096 - JP 2014500723-A/17599: Polycomb-Associated Non-Coding RNAs.LF334593 - JP 2014500723-A/142096: Polycomb-Associated Non-Coding RNAs.LF334594 - JP 2014500723-A/142097: Polycomb-Associated Non-Coding RNAs.LF334595 - JP 2014500723-A/142098: Polycomb-Associated Non-Coding RNAs.JD343589 - Sequence 324613 from Patent EP1572962.JD207843 - Sequence 188867 from Patent EP1572962.JD073804 - Sequence 54828 from Patent EP1572962.MA570166 - JP 2018138019-A/142092: Polycomb-Associated Non-Coding RNAs.MA570167 - JP 2018138019-A/142093: Polycomb-Associated Non-Coding RNAs.MA570168 - JP 2018138019-A/142094: Polycomb-Associated Non-Coding RNAs.MA570169 - JP 2018138019-A/142095: Polycomb-Associated Non-Coding RNAs.MA445673 - JP 2018138019-A/17599: Polycomb-Associated Non-Coding RNAs.MA570170 - JP 2018138019-A/142096: Polycomb-Associated Non-Coding RNAs.MA570171 - JP 2018138019-A/142097: Polycomb-Associated Non-Coding RNAs.MA570172 - JP 2018138019-A/142098: Polycomb-Associated Non-Coding RNAs.
Other Names for This Gene
Alternate Gene Symbols: AK291680, KHNYN_HUMAN, KIAA0323, NM_015299, NP_056114, O15037, Q86TZ6, Q8IUQ2, Q96BA9UCSC ID: uc010alw.3RefSeq Accession: NM_015299
Protein: O15037
(aka KHNYN_HUMAN)
CCDS: CCDS32058.1
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
AK291680.1
exon count:
8 CDS single in 3' UTR:
no
RNA size:
2424
ORF size:
2037 CDS single in intron:
no
Alignment % ID:
99.71
txCdsPredict score:
4231.00 frame shift in genome:
no
% Coverage:
100.00
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
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Methods, Credits, and Use Restrictions
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