Description: Homo sapiens NADH dehydrogenase (ubiquinone) complex I, assembly factor 1 (NDUFAF1), transcript variant 2, non-coding RNA. RefSeq Summary (NR_045620): This gene encodes a complex I assembly factor protein. Complex I (NADH-ubiquinone oxidoreductase) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. The encoded protein is required for assembly of complex I, and mutations in this gene are a cause of mitochondrial complex I deficiency. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 19. [provided by RefSeq, Dec 2011]. Transcript (Including UTRs) Position: hg19 chr15:41,679,547-41,694,658 Size: 15,112 Total Exon Count: 6 Strand: -
Press "+" in the title bar above to open this section.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse
Rat
Zebrafish
D. melanogaster
C. elegans
S. cerevisiae
No ortholog
No ortholog
No ortholog
No ortholog
No ortholog
No ortholog
Descriptions from all associated GenBank mRNAs
AF151823 - Homo sapiens CGI-65 protein mRNA, complete cds. BC000780 - Homo sapiens NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1, mRNA (cDNA clone MGC:707 IMAGE:3504355), complete cds. KJ893811 - Synthetic construct Homo sapiens clone ccsbBroadEn_03205 NDUFAF1 gene, encodes complete protein. KR709794 - Synthetic construct Homo sapiens clone CCSBHm_00006121 NDUFAF1 (NDUFAF1) mRNA, encodes complete protein. AB463915 - Synthetic construct DNA, clone: pF1KB6479, Homo sapiens NDUFAF1 gene for NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1, without stop codon, in Flexi system. AK310983 - Homo sapiens cDNA, FLJ18025. JD072749 - Sequence 53773 from Patent EP1572962. AK309889 - Homo sapiens cDNA, FLJ99930. JD208951 - Sequence 189975 from Patent EP1572962. JD179345 - Sequence 160369 from Patent EP1572962. JD481243 - Sequence 462267 from Patent EP1572962. AK310033 - Homo sapiens cDNA, FLJ17075. JD026362 - Sequence 7386 from Patent EP1572962. JD028689 - Sequence 9713 from Patent EP1572962.