Human Gene CEACAM20 (uc010ejq.1)
  Description: Homo sapiens carcinoembryonic antigen-related cell adhesion molecule 20 (CEACAM20), transcript variant 4S, mRNA.
Transcript (Including UTRs)
   Position: hg19 chr19:45,010,211-45,033,548 Size: 23,338 Total Exon Count: 11 Strand: -
Coding Region
   Position: hg19 chr19:45,010,213-45,033,532 Size: 23,320 Coding Exon Count: 11 

Page IndexSequence and LinksPrimersGenetic AssociationsCTDGene Alleles
Microarray ExpressionRNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther Names
Model InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr19:45,010,211-45,033,548)mRNA (may differ from genome)Protein (491 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCLynxMGIPubMedUniProtKBBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database (archive): CEACAM20
CDC HuGE Published Literature: CEACAM20
Positive Disease Associations: Tunica Media
Related Studies:
  1. Tunica Media
    , , . [PubMed 0]
  2. Tunica Media
    , , . [PubMed 0]

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -1.8016-0.112 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR007110 - Ig-like
IPR013783 - Ig-like_fold
IPR013098 - Ig_I-set
IPR003599 - Ig_sub
IPR003598 - Ig_sub2

Pfam Domains:
PF00047 - Immunoglobulin domain
PF07679 - Immunoglobulin I-set domain
PF13895 - Immunoglobulin domain
PF13927 - Immunoglobulin domain

SCOP Domains:
48726 - Immunoglobulin

ModBase Predicted Comparative 3D Structure on A7LFK8
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
      
      
      

-  Descriptions from all associated GenBank mRNAs
  AY358129 - Homo sapiens clone DNA211193 GPAD9366 (UNQ9366) mRNA, complete cds.
EU008600 - Homo sapiens carcinoembryonic antigen-related cell adhesion molecule 20 variant 5L (CEACAM20) mRNA, complete cds, alternatively spliced.
EU008601 - Homo sapiens carcinoembryonic antigen-related cell adhesion molecule 20 variant 4S (CEACAM20) mRNA, complete cds, alternatively spliced.
EU008602 - Homo sapiens carcinoembryonic antigen-related cell adhesion molecule 20 variant 4L (CEACAM20) mRNA, complete cds, alternatively spliced.
EU008603 - Homo sapiens carcinoembryonic antigen-related cell adhesion molecule 20 variant 5S (CEACAM20) mRNA, complete cds, alternatively spliced.
BC172298 - Synthetic construct Homo sapiens clone IMAGE:100068992, MGC:199003 carcinoembryonic antigen-related cell adhesion molecule 20 (CEACAM20) mRNA, encodes complete protein.

-  Other Names for This Gene
  Alternate Gene Symbols: A7LFK8, A7LFK8_HUMAN, NM_001102598, NP_001096068
UCSC ID: uc010ejq.1
RefSeq Accession: NM_001102598
Protein: A7LFK8

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_001102598.1
exon count: 10CDS single in 3' UTR: no RNA size: 1494
ORF size: 1477CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 2169.00frame shift in genome: yes % Coverage: 99.93
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.