Human Gene TMPRSS7 (uc010hqb.2)
Description: Homo sapiens transmembrane protease, serine 7 (TMPRSS7), transcript variant 1, mRNA.
Transcript (Including UTRs)
Position: hg19 chr3:111,758,465-111,800,116 Size: 41,652 Total Exon Count: 16 Strand: +
Coding Region
Position: hg19 chr3:111,760,805-111,799,931 Size: 39,127 Coding Exon Count: 15
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Primer design for this transcript
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
Pfam Domains: PF00057 - Low-density lipoprotein receptor domain class A
PF00089 - Trypsin
PF00431 - CUB domain
PF01390 - SEA domain
SCOP Domains: 49854 - Spermadhesin, CUB domain
50494 - Trypsin-like serine proteases
82671 - SEA domain
57424 - LDL receptor-like module
ModBase Predicted Comparative 3D Structure on Q7RTY8-2
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Descriptions from all associated GenBank mRNAs
KJ904213 - Synthetic construct Homo sapiens clone ccsbBroadEn_13607 TMPRSS7 gene, encodes complete protein.HQ258472 - Synthetic construct Homo sapiens clone IMAGE:100072901 Unknown protein gene, encodes complete protein.AK131211 - Homo sapiens cDNA FLJ16088 fis, clone NT2RP7008435, weakly similar to EPITHIN (EC 3.4.21.-).BC117322 - Homo sapiens transmembrane protease, serine 7, mRNA (cDNA clone MGC:150931 IMAGE:40125873), complete cds.JD307234 - Sequence 288258 from Patent EP1572962.JD323198 - Sequence 304222 from Patent EP1572962.JD353559 - Sequence 334583 from Patent EP1572962.JD088173 - Sequence 69197 from Patent EP1572962.JD550730 - Sequence 531754 from Patent EP1572962.JD184978 - Sequence 166002 from Patent EP1572962.JD501766 - Sequence 482790 from Patent EP1572962.JD361035 - Sequence 342059 from Patent EP1572962.JD141433 - Sequence 122457 from Patent EP1572962.JD172981 - Sequence 154005 from Patent EP1572962.JD539750 - Sequence 520774 from Patent EP1572962.JD511031 - Sequence 492055 from Patent EP1572962.JD259220 - Sequence 240244 from Patent EP1572962.JD349535 - Sequence 330559 from Patent EP1572962.JD063536 - Sequence 44560 from Patent EP1572962.JD372608 - Sequence 353632 from Patent EP1572962.JD301599 - Sequence 282623 from Patent EP1572962.JD233703 - Sequence 214727 from Patent EP1572962.JD245836 - Sequence 226860 from Patent EP1572962.JD378613 - Sequence 359637 from Patent EP1572962.JD052949 - Sequence 33973 from Patent EP1572962.JD300164 - Sequence 281188 from Patent EP1572962.JD104726 - Sequence 85750 from Patent EP1572962.JD427350 - Sequence 408374 from Patent EP1572962.JD499746 - Sequence 480770 from Patent EP1572962.JD371016 - Sequence 352040 from Patent EP1572962.JD368086 - Sequence 349110 from Patent EP1572962.JD060824 - Sequence 41848 from Patent EP1572962.JD483926 - Sequence 464950 from Patent EP1572962.JD231319 - Sequence 212343 from Patent EP1572962.JD482163 - Sequence 463187 from Patent EP1572962.JD060501 - Sequence 41525 from Patent EP1572962.JD275574 - Sequence 256598 from Patent EP1572962.JD552002 - Sequence 533026 from Patent EP1572962.JD486961 - Sequence 467985 from Patent EP1572962.JD491801 - Sequence 472825 from Patent EP1572962.JD512689 - Sequence 493713 from Patent EP1572962.JD071235 - Sequence 52259 from Patent EP1572962.JD446351 - Sequence 427375 from Patent EP1572962.
Other Names for This Gene
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
NM_001042575.2
exon count:
16 CDS single in 3' UTR:
no
RNA size:
2509
ORF size:
2154 CDS single in intron:
no
Alignment % ID:
100.00
txCdsPredict score:
4356.00 frame shift in genome:
no
% Coverage:
100.00
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
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Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.