Description: Homo sapiens PR domain containing 5 (PRDM5), mRNA. RefSeq Summary (NM_018699): The protein encoded by this gene is a transcription factor of the PR-domain protein family. It contains a PR-domain and multiple zinc finger motifs. Transcription factors of the PR-domain family are known to be involved in cell differentiation and tumorigenesis. [provided by RefSeq, Jul 2008]. Sequence Note:. Transcript (Including UTRs) Position: hg19 chr4:121,737,218-121,844,013 Size: 106,796 Total Exon Count: 6 Strand: - Coding Region Position: hg19 chr4:121,737,453-121,843,763 Size: 106,311 Coding Exon Count: 6
Blood Glucose James B Meigs et al. BMC medical genetics 2007, Genome-wide association with diabetes-related traits in the Framingham Heart Study., BMC medical genetics.
[PubMed 17903298]
Framingham 100K SNP data is a resource for association tests of known and novel genes with diabetes and related traits posted at http://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?id=phs000007 webcite. Framingham 100K data replicate the TCF7L2 association with diabetes.
fasting plasma glucose Meigs ,et al. 2007, Genome-wide association with diabetes-related traits in the Framingham Heart Study, BMC medical genetics 2007 8 Suppl 1 : S16.
[PubMed 17903298]
fasting plasma glucose Meigs ,et al. 2007, Genome-wide association with diabetes-related traits in the Framingham Heart Study, BMC medical genetics 2007 8 Suppl 1 : S16.
[PubMed 17903298]
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
SCOP Domains: 82199 - SET domain 57667 - C2H2 and C2HC zinc fingers
ModBase Predicted Comparative 3D Structure on Q0VAI9
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.