Description: Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 19 (ADAMTS19), mRNA. RefSeq Summary (NM_133638): This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has high sequence similarity to the protein encoded by ADAMTS16, another family member. [provided by RefSeq, Jul 2008]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Transcript (Including UTRs) Position: hg19 chr5:128,932,252-129,074,376 Size: 142,125 Total Exon Count: 17 Strand: +
Sexual Dysfunctions, Psychological Kouichi Kurose et al. Psychiatry research 2012, Genome-wide association study of SSRI/SNRI-induced sexual dysfunction in a Japanese cohort with major depression., Psychiatry research.
[PubMed 22445761]
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse
Rat
Zebrafish
D. melanogaster
C. elegans
S. cerevisiae
No ortholog
No ortholog
No ortholog
No ortholog
No ortholog
No ortholog
Descriptions from all associated GenBank mRNAs
BC156492 - Synthetic construct Homo sapiens clone IMAGE:100063096, MGC:190688 ADAM metallopeptidase with thrombospondin type 1 motif, 19 (ADAMTS19) mRNA, encodes complete protein. AJ311904 - Homo sapiens mRNA for ADAMTS19 protein (ADAMTS19 gene). AK128729 - Homo sapiens cDNA FLJ46897 fis, clone UTERU3021850, weakly similar to ADAM-TS 7 precursor (EC 3.4.24.-). AK122622 - Homo sapiens cDNA FLJ16042 fis, clone BRAMY2021498, highly similar to ADAMTS-19 precursor (EC 3.4.24.-).