Human Gene TRIM26 (uc010jry.3)
Description: Homo sapiens tripartite motif containing 26 (TRIM26), transcript variant 1, mRNA.
RefSeq Summary (NM_003449): The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Although the function of the protein is unknown, the RING domain suggests that the protein may have DNA-binding activity. The gene localizes to the major histocompatibility complex (MHC) class I region on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2011].
Transcript (Including UTRs)
Position: hg19 chr6:30,152,232-30,181,271 Size: 29,040 Total Exon Count: 9 Strand: -
Coding Region
Position: hg19 chr6:30,153,653-30,157,070 Size: 3,418 Coding Exon Count: 2
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Primer design for this transcript
Genetic Association Studies of Complex Diseases and Disorders
Genetic Association Database (archive): TRIM26
CDC HuGE Published Literature: TRIM26
Positive Disease Associations: Behcet Syndrome
, Lupus Erythematosus, Systemic
, Multiple Sclerosis
, Schizophrenia
Related Studies: Behcet Syndrome Elaine F Remmers et al. Nature genetics 2010, , Nature genetics.
[PubMed 20622878 ]
Behcet Syndrome Elaine F Remmers et al. Nature genetics 2010, , Nature genetics.
[PubMed 20622878 ]
Behcet Syndrome Elaine F Remmers et al. Nature genetics 2010, , Nature genetics.
[PubMed 20622878 ]
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MalaCards Disease Associations
Comparative Toxicogenomics Database (CTD)
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Descriptions from all associated GenBank mRNAs
BC021115 - Homo sapiens tripartite motif-containing 26, mRNA (cDNA clone IMAGE:5094007), with apparent retained intron.BC032297 - Homo sapiens tripartite motif-containing 26, mRNA (cDNA clone MGC:40232 IMAGE:4938971), complete cds.BC024039 - Homo sapiens tripartite motif-containing 26, mRNA (cDNA clone MGC:12710 IMAGE:3954669), complete cds.JD079105 - Sequence 60129 from Patent EP1572962.JD242391 - Sequence 223415 from Patent EP1572962.JD345828 - Sequence 326852 from Patent EP1572962.U09825 - Human acid finger protein mRNA, complete cds.AK122859 - Homo sapiens cDNA FLJ16483 fis, clone BRTHA3002265, highly similar to Human acid finger protein mRNA.AK096996 - Homo sapiens cDNA FLJ39677 fis, clone SMINT2009973, highly similar to Human acid finger protein mRNA.JD274816 - Sequence 255840 from Patent EP1572962.JD281163 - Sequence 262187 from Patent EP1572962.JD363854 - Sequence 344878 from Patent EP1572962.JD233352 - Sequence 214376 from Patent EP1572962.JD428045 - Sequence 409069 from Patent EP1572962.JD362724 - Sequence 343748 from Patent EP1572962.JD122869 - Sequence 103893 from Patent EP1572962.JD415656 - Sequence 396680 from Patent EP1572962.JD096159 - Sequence 77183 from Patent EP1572962.JD043040 - Sequence 24064 from Patent EP1572962.JD496609 - Sequence 477633 from Patent EP1572962.JD152630 - Sequence 133654 from Patent EP1572962.JD375884 - Sequence 356908 from Patent EP1572962.JD267360 - Sequence 248384 from Patent EP1572962.JD540658 - Sequence 521682 from Patent EP1572962.JD325044 - Sequence 306068 from Patent EP1572962.JD164767 - Sequence 145791 from Patent EP1572962.JD206115 - Sequence 187139 from Patent EP1572962.JD181311 - Sequence 162335 from Patent EP1572962.LF341396 - JP 2014500723-A/148899: Polycomb-Associated Non-Coding RNAs.JD539442 - Sequence 520466 from Patent EP1572962.JD508696 - Sequence 489720 from Patent EP1572962.JD325653 - Sequence 306677 from Patent EP1572962.JD478996 - Sequence 460020 from Patent EP1572962.JD147881 - Sequence 128905 from Patent EP1572962.JD439564 - Sequence 420588 from Patent EP1572962.AK314782 - Homo sapiens cDNA, FLJ95652.LF341395 - JP 2014500723-A/148898: Polycomb-Associated Non-Coding RNAs.LF341394 - JP 2014500723-A/148897: Polycomb-Associated Non-Coding RNAs.LF341393 - JP 2014500723-A/148896: Polycomb-Associated Non-Coding RNAs.LF341392 - JP 2014500723-A/148895: Polycomb-Associated Non-Coding RNAs.CU689318 - Synthetic construct Homo sapiens gateway clone IMAGE:100019819 5' read TRIM26 mRNA.LF341391 - JP 2014500723-A/148894: Polycomb-Associated Non-Coding RNAs.JD364926 - Sequence 345950 from Patent EP1572962.JD133366 - Sequence 114390 from Patent EP1572962.JD322329 - Sequence 303353 from Patent EP1572962.MA576973 - JP 2018138019-A/148899: Polycomb-Associated Non-Coding RNAs.MA576972 - JP 2018138019-A/148898: Polycomb-Associated Non-Coding RNAs.MA576971 - JP 2018138019-A/148897: Polycomb-Associated Non-Coding RNAs.MA576970 - JP 2018138019-A/148896: Polycomb-Associated Non-Coding RNAs.MA576969 - JP 2018138019-A/148895: Polycomb-Associated Non-Coding RNAs.MA576968 - JP 2018138019-A/148894: Polycomb-Associated Non-Coding RNAs.
Other Names for This Gene
Alternate Gene Symbols: AK314782UCSC ID: uc010jry.3RefSeq Accession: NM_003449
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
AK314782.1
exon count:
9 CDS single in 3' UTR:
no
RNA size:
2165
ORF size:
810 CDS single in intron:
no
Alignment % ID:
99.72
txCdsPredict score:
1050.50 frame shift in genome:
no
% Coverage:
100.00
has start codon:
yes
stop codon in genome:
no
# of Alignments:
8
has end codon:
yes
retained intron:
yes
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
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Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.