Human Gene MOGAT3 (uc010lhr.3)
Description: Homo sapiens monoacylglycerol O-acyltransferase 3 (MOGAT3), mRNA.
RefSeq Summary (NM_178176): Acyl-CoA:monoacylglycerol acyltransferase (MOGAT; EC 2.3.1.22) catalyzes the synthesis of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA (Cheng et al., 2003 [PubMed 12618427]).[supplied by OMIM, Mar 2008].
Transcript (Including UTRs)
Position: hg19 chr7:100,839,013-100,844,302 Size: 5,290 Total Exon Count: 6 Strand: -
Coding Region
Position: hg19 chr7:100,839,204-100,844,135 Size: 4,932 Coding Exon Count: 6
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Primer design for this transcript
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
Common Gene Haplotype Alleles
Press "+" in the title bar above to open this section.
RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
Press "+" in the title bar above to open this section.
mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
Pfam Domains: PF03982 - Diacylglycerol acyltransferase
ModBase Predicted Comparative 3D Structure on Q86VF5-2
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Descriptions from all associated GenBank mRNAs
JD277586 - Sequence 258610 from Patent EP1572962.AY229854 - Homo sapiens acyl coenzyme A:monoacylglycerol acyltransferase 3 (MGAT3) mRNA, complete cds.JD277585 - Sequence 258609 from Patent EP1572962.JD118527 - Sequence 99551 from Patent EP1572962.JD118528 - Sequence 99552 from Patent EP1572962.JD332088 - Sequence 313112 from Patent EP1572962.JD443015 - Sequence 424039 from Patent EP1572962.JD558825 - Sequence 539849 from Patent EP1572962.JD564634 - Sequence 545658 from Patent EP1572962.JD257914 - Sequence 238938 from Patent EP1572962.JD178699 - Sequence 159723 from Patent EP1572962.JD373786 - Sequence 354810 from Patent EP1572962.JD362370 - Sequence 343394 from Patent EP1572962.JD387693 - Sequence 368717 from Patent EP1572962.JD216510 - Sequence 197534 from Patent EP1572962.AY358200 - Homo sapiens clone DNA213516 GVAT9383 (UNQ9383) mRNA, complete cds.JD474124 - Sequence 455148 from Patent EP1572962.JD044705 - Sequence 25729 from Patent EP1572962.JD361879 - Sequence 342903 from Patent EP1572962.JD456490 - Sequence 437514 from Patent EP1572962.BC100953 - Homo sapiens monoacylglycerol O-acyltransferase 3, mRNA (cDNA clone MGC:119202 IMAGE:40004561), complete cds.BC100954 - Homo sapiens monoacylglycerol O-acyltransferase 3, mRNA (cDNA clone MGC:119203 IMAGE:40004562), complete cds.BC100955 - Homo sapiens monoacylglycerol O-acyltransferase 3, mRNA (cDNA clone MGC:119204 IMAGE:40004564), complete cds.JD288389 - Sequence 269413 from Patent EP1572962.KJ900658 - Synthetic construct Homo sapiens clone ccsbBroadEn_10052 MOGAT3 gene, encodes complete protein.KJ904216 - Synthetic construct Homo sapiens clone ccsbBroadEn_13610 MOGAT3 gene, encodes complete protein.JD077143 - Sequence 58167 from Patent EP1572962.JD409347 - Sequence 390371 from Patent EP1572962.
Biochemical and Signaling Pathways
Other Names for This Gene
Alternate Gene Symbols: BC100955, DC7, DGAT2L7, Q86VF5-2, UNQ9383/PRO34208UCSC ID: uc010lhr.3RefSeq Accession: NM_178176
Protein: Q86VF5-2 , splice isoform of Q86VF5
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
BC100955.1
exon count:
6 CDS single in 3' UTR:
no
RNA size:
933
ORF size:
846 CDS single in intron:
no
Alignment % ID:
100.00
txCdsPredict score:
1757.00 frame shift in genome:
no
% Coverage:
99.68
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
Click here
for a detailed description of the fields of the table above.
Methods, Credits, and Use Restrictions
Click here
for details on how this gene model was made and data restrictions if any.