Human Gene ZFAND1 (uc010lzx.2)
  Description: Homo sapiens zinc finger, AN1-type domain 1 (ZFAND1), transcript variant 2, mRNA.
Transcript (Including UTRs)
   Position: hg19 chr8:82,613,566-82,633,539 Size: 19,974 Total Exon Count: 8 Strand: -
Coding Region
   Position: hg19 chr8:82,614,930-82,633,516 Size: 18,587 Coding Exon Count: 8 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther SpeciesmRNA Descriptions
Other NamesModel InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr8:82,613,566-82,633,539)mRNA (may differ from genome)Protein (261 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsH-INV
HGNCLynxMGIPubMedUniProtKBBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: E5RIG0_HUMAN
DESCRIPTION: SubName: Full=AN1-type zinc finger protein 1;
CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 18.65 RPKM in Ovary
Total median expression: 573.45 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -5.3023-0.230 Picture PostScript Text
3' UTR -328.141364-0.241 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR000058 - Znf_AN1

Pfam Domains:
PF01428 - AN1-like Zinc finger

ModBase Predicted Comparative 3D Structure on E5RIG0
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
      
      
      

-  Descriptions from all associated GenBank mRNAs
  AL833030 - Homo sapiens mRNA; cDNA DKFZp666I148 (from clone DKFZp666I148).
LF206076 - JP 2014500723-A/13579: Polycomb-Associated Non-Coding RNAs.
BC051857 - Homo sapiens zinc finger, AN1-type domain 1, mRNA (cDNA clone MGC:60212 IMAGE:6012307), complete cds.
BC056877 - Homo sapiens zinc finger, AN1-type domain 1, mRNA (cDNA clone MGC:64953 IMAGE:6140929), complete cds.
AK225195 - Homo sapiens mRNA for AN1-type zinc finger protein 1 variant, clone: COL01020.
AK024069 - Homo sapiens cDNA FLJ14007 fis, clone Y79AA1002407.
JD251361 - Sequence 232385 from Patent EP1572962.
JD350390 - Sequence 331414 from Patent EP1572962.
JD509982 - Sequence 491006 from Patent EP1572962.
AK304111 - Homo sapiens cDNA FLJ52833 complete cds, highly similar to AN1-type zinc finger protein 1.
BC022251 - Homo sapiens zinc finger, AN1-type domain 1, mRNA (cDNA clone MGC:22190 IMAGE:4695118), complete cds.
JD299502 - Sequence 280526 from Patent EP1572962.
JD561712 - Sequence 542736 from Patent EP1572962.
JD372103 - Sequence 353127 from Patent EP1572962.
JD511201 - Sequence 492225 from Patent EP1572962.
JD309216 - Sequence 290240 from Patent EP1572962.
HQ447700 - Synthetic construct Homo sapiens clone IMAGE:100071028; CCSB012998_01 zinc finger, AN1-type domain 1 (ZFAND1) gene, encodes complete protein.
CR457323 - Homo sapiens full open reading frame cDNA clone RZPDo834G0313D for gene FLJ14007, hypothetical protein FLJ14007; complete cds, incl. stopcodon.
MA441653 - JP 2018138019-A/13579: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: E5RIG0, E5RIG0_HUMAN, NM_001170796, NP_001164267
UCSC ID: uc010lzx.2
RefSeq Accession: NM_001170796
Protein: E5RIG0 CCDS: CCDS6232.1, CCDS55251.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_001170796.1
exon count: 8CDS single in 3' UTR: no RNA size: 2189
ORF size: 786CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 1772.00frame shift in genome: no % Coverage: 99.27
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.