Human Gene TRIQK (uc010map.3)
  Description: Homo sapiens triple QxxK/R motif containing (TRIQK), transcript variant 2, mRNA.
Transcript (Including UTRs)
   Position: hg19 chr8:93,895,758-93,978,372 Size: 82,615 Total Exon Count: 5 Strand: -
Coding Region
   Position: hg19 chr8:93,898,850-93,929,217 Size: 30,368 Coding Exon Count: 3 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther SpeciesGO Annotations
mRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr8:93,895,758-93,978,372)mRNA (may differ from genome)Protein (86 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsH-INV
HGNCLynxMGIneXtProtPubMedUniProtKB
BioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: TRIQK_HUMAN
DESCRIPTION: RecName: Full=Triple QxxK/R motif-containing protein; AltName: Full=Triple repetitive-sequence of QXXK/R protein homolog;
FUNCTION: May play a role in cell growth and maintenance of cell morphology (By similarity).
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Single-pass membrane protein.
SIMILARITY: Belongs to the TRIQK family.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene
  • C532162 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine
  • D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
  • D008627 Mercuric Chloride
  • D015215 Zidovudine
  • C088658 zoledronic acid

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 2.39 RPKM in Cells - Cultured fibroblasts
Total median expression: 55.68 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -95.39318-0.300 Picture PostScript Text
3' UTR -735.383092-0.238 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR024842 - TRIQK

Pfam Domains:
PF15168 - Triple QxxK/R motif-containing protein family

ModBase Predicted Comparative 3D Structure on Q629K1
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGD    
 Protein Sequence    
 Alignment    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Cellular Component:
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane


-  Descriptions from all associated GenBank mRNAs
  CR749421 - Homo sapiens mRNA; cDNA DKFZp779L1068 (from clone DKFZp779L1068).
BC110326 - Homo sapiens cDNA clone IMAGE:5555490.
BC065838 - Homo sapiens cDNA clone IMAGE:30385138, partial cds.
AK097956 - Homo sapiens cDNA FLJ40637 fis, clone THYMU2015984.
DQ351291 - Homo sapiens triqk mRNA, complete cds.
BC031029 - Homo sapiens cDNA clone IMAGE:4723870.
AK096398 - Homo sapiens cDNA FLJ39079 fis, clone NT2RP7018032.
BC104255 - Homo sapiens chromosome 8 open reading frame 83, mRNA (cDNA clone IMAGE:40035935).
BC104254 - Homo sapiens chromosome 8 open reading frame 83, mRNA (cDNA clone IMAGE:40035934).
BC113007 - Homo sapiens chromosome 8 open reading frame 83, mRNA (cDNA clone IMAGE:40035932).
BC113008 - Homo sapiens chromosome 8 open reading frame 83, mRNA (cDNA clone IMAGE:40035933).

-  Other Names for This Gene
  Alternate Gene Symbols: C8orf83, NM_001171797, NP_001177965, Q629K1, TRIQK_HUMAN
UCSC ID: uc010map.3
RefSeq Accession: NM_001171797
Protein: Q629K1 (aka TRIQK_HUMAN)
CCDS: CCDS55261.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_001171797.1
exon count: 5CDS single in 3' UTR: no RNA size: 3687
ORF size: 261CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 698.00frame shift in genome: no % Coverage: 99.57
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.