Human Gene GTF3C4 (uc010mzw.3)
  Description: Homo sapiens general transcription factor IIIC, polypeptide 4, 90kDa (GTF3C4), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr9:135,545,728-135,565,470 Size: 19,743 Total Exon Count: 6 Strand: +


Page IndexSequence and LinksPrimersGenetic AssociationsCTDRNA-Seq Expression
Microarray ExpressionOther SpeciesmRNA DescriptionsPathwaysOther NamesModel Information
Methods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr9:135,545,728-135,565,470)mRNA (may differ from genome)No protein
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
BioGPSEnsemblExonPrimerGeneNetworkH-INVHGNC
LynxPubMedTreefamWikipedia

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database (archive): GTF3C4
CDC HuGE Published Literature: GTF3C4
Positive Disease Associations: Schizophrenia
Related Studies:
  1. Schizophrenia
    , , . [PubMed 0]

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 8.34 RPKM in Brain - Cerebellar Hemisphere
Total median expression: 189.99 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  BC060821 - Homo sapiens general transcription factor IIIC, polypeptide 4, 90kDa, mRNA (cDNA clone IMAGE:4825930), with apparent retained intron.
AF142328 - Homo sapiens transcription factor IIIC90 mRNA, complete cds.
JD429961 - Sequence 410985 from Patent EP1572962.
JD556807 - Sequence 537831 from Patent EP1572962.
BC094774 - Homo sapiens general transcription factor IIIC, polypeptide 4, 90kDa, mRNA (cDNA clone MGC:104675 IMAGE:4830453), complete cds.
BC011619 - Homo sapiens general transcription factor IIIC, polypeptide 4, 90kDa, mRNA (cDNA clone IMAGE:3960260), partial cds.
BC022787 - Homo sapiens general transcription factor IIIC, polypeptide 4, 90kDa, mRNA (cDNA clone IMAGE:3845225), partial cds.
JD426382 - Sequence 407406 from Patent EP1572962.
BC104755 - Homo sapiens general transcription factor IIIC, polypeptide 4, 90kDa, mRNA (cDNA clone MGC:132415 IMAGE:8143758), complete cds.
BC112245 - Homo sapiens general transcription factor IIIC, polypeptide 4, 90kDa, mRNA (cDNA clone MGC:138450 IMAGE:8327713), complete cds.
DQ583454 - Homo sapiens piRNA piR-50566, complete sequence.
JD440460 - Sequence 421484 from Patent EP1572962.
AB529214 - Synthetic construct DNA, clone: pF1KB0410, Homo sapiens GTF3C4 gene for general transcription factor IIIC, polypeptide 4, 90kDa, without stop codon, in Flexi system.
KJ897996 - Synthetic construct Homo sapiens clone ccsbBroadEn_07390 GTF3C4 gene, encodes complete protein.
AK024655 - Homo sapiens cDNA: FLJ21002 fis, clone CAE03545, highly similar to AF142328 Homo sapiens transcription factor IIIC90 mRNA.
AK027509 - Homo sapiens cDNA FLJ14603 fis, clone NT2RP1000357, highly similar to General transcription factor 3C polypeptide 4 (EC 2.3.1.48).
AK126436 - Homo sapiens cDNA FLJ44472 fis, clone UTERU2029742.
JD170547 - Sequence 151571 from Patent EP1572962.
JD203102 - Sequence 184126 from Patent EP1572962.
AJ420451 - Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 909091.
JD308665 - Sequence 289689 from Patent EP1572962.
DQ581889 - Homo sapiens piRNA piR-50001, complete sequence.
AF086460 - Homo sapiens full length insert cDNA clone ZD85A02.

-  Biochemical and Signaling Pathways
  BioCarta from NCI Cancer Genome Anatomy Project
h_RNApol3Pathway - RNA polymerase III transcription

-  Other Names for This Gene
  Alternate Gene Symbols: BC060821
UCSC ID: uc010mzw.3
RefSeq Accession: NM_012204

-  Gene Model Information
 
category: nearCoding nonsense-mediated-decay: yes RNA accession: BC060821.1
exon count: 6CDS single in 3' UTR: no RNA size: 3579
ORF size: 0CDS single in intron: no Alignment % ID: 99.97
txCdsPredict score: 4258.00frame shift in genome: no % Coverage: 91.03
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.