Description: Homo sapiens solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (SLC6A8), transcript variant 3, mRNA. RefSeq Summary (NM_001142806): The protein encoded by this gene is a plasma membrane protein whose function is to transport creatine into and out of cells. Defects in this gene can result in X-linked creatine deficiency syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]. Transcript (Including UTRs) Position: hg19 chrX:152,955,814-152,958,247 Size: 2,434 Total Exon Count: 3 Strand: + Coding Region Position: hg19 chrX:152,955,913-152,957,961 Size: 2,049 Coding Exon Count: 3
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse
Rat
Zebrafish
D. melanogaster
C. elegans
S. cerevisiae
No ortholog
No ortholog
No ortholog
No ortholog
No ortholog
No ortholog
Descriptions from all associated GenBank mRNAs
LF211523 - JP 2014500723-A/19026: Polycomb-Associated Non-Coding RNAs. L31409 - Homo sapiens creatine transporter mRNA, complete cds. BC081558 - Homo sapiens solute carrier family 6 (neurotransmitter transporter, creatine), member 8, mRNA (cDNA clone MGC:87396 IMAGE:4823748), complete cds. MA447100 - JP 2018138019-A/19026: Polycomb-Associated Non-Coding RNAs. AB209704 - Homo sapiens mRNA for solute carrier family 6 (neurotransmitter transporter, creatine), member 8 variant protein. S74039 - Homo sapiens creatine transporter (creatine transporter, hCRT-BS2M) mRNA, complete cds. BC012355 - Homo sapiens solute carrier family 6 (neurotransmitter transporter, creatine), member 8, mRNA (cDNA clone MGC:20403 IMAGE:4634609), complete cds. DQ892306 - Synthetic construct clone IMAGE:100004936; FLH185069.01X; RZPDo839E11146D solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (SLC6A8) gene, encodes complete protein. DQ895505 - Synthetic construct Homo sapiens clone IMAGE:100009965; FLH185065.01L; RZPDo839E11145D solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (SLC6A8) gene, encodes complete protein. KJ534942 - Homo sapiens clone SLC6A8_iso-D_adult-A01 solute carrier family 6 member 8 isoform D (SLC6A8) mRNA, partial cds, alternatively spliced. KJ534943 - Homo sapiens clone SLC6A8_iso-A_adult-A04 solute carrier family 6 member 8 isoform A (SLC6A8) mRNA, partial cds, alternatively spliced. KJ534944 - Homo sapiens clone SLC6A8_iso-B_fetal-F05 solute carrier family 6 member 8 isoform B (SLC6A8) mRNA, partial cds, alternatively spliced. KJ534945 - Homo sapiens clone SLC6A8_iso-C_fetal-F11 solute carrier family 6 member 8 isoform C (SLC6A8) mRNA, partial cds, alternatively spliced. AK295495 - Homo sapiens cDNA FLJ51860 complete cds, highly similar to Sodium-and chloride-dependent creatinetransporter 1. AK309060 - Homo sapiens cDNA, FLJ99101. JD239175 - Sequence 220199 from Patent EP1572962. JD497194 - Sequence 478218 from Patent EP1572962. JD420355 - Sequence 401379 from Patent EP1572962. JD541082 - Sequence 522106 from Patent EP1572962. JD432841 - Sequence 413865 from Patent EP1572962. LF380729 - JP 2014500723-A/188232: Polycomb-Associated Non-Coding RNAs. KC800563 - Homo sapiens creatine transporter SLC6A8 variant D (SLC6A8) mRNA, complete cds, alternatively spliced. EU280316 - Homo sapiens creatine transporter SLC6A8 splice variant C (SLC6A8) mRNA, complete cds, alternatively spliced. U17986 - Human GABA/noradrenaline transporter mRNA, complete cds. LF380730 - JP 2014500723-A/188233: Polycomb-Associated Non-Coding RNAs. MA616306 - JP 2018138019-A/188232: Polycomb-Associated Non-Coding RNAs. MA616307 - JP 2018138019-A/188233: Polycomb-Associated Non-Coding RNAs.