Human Gene ANGEL2 (uc010pto.2)
Description: Homo sapiens angel homolog 2 (Drosophila) (ANGEL2), mRNA.
Transcript (Including UTRs)
Position: hg19 chr1:213,165,524-213,188,820 Size: 23,297 Total Exon Count: 9 Strand: -
Coding Region
Position: hg19 chr1:213,168,383-213,184,556 Size: 16,174 Coding Exon Count: 8
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: F5H476_HUMAN
DESCRIPTION: SubName: Full=Protein angel homolog 2;
CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
Primer design for this transcript
Comparative Toxicogenomics Database (CTD)
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR005135 - Endo/exonuclease/phosphatase
Pfam Domains: PF03372 - Endonuclease/Exonuclease/phosphatase family
SCOP Domains: 56219 - DNase I-like
ModBase Predicted Comparative 3D Structure on F5H476
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse Rat Zebrafish D. melanogaster C. elegans S. cerevisiae
No ortholog No ortholog No ortholog No ortholog No ortholog No ortholog
Gene Details
Gene Sorter
Descriptions from all associated GenBank mRNAs
BC047469 - Homo sapiens angel homolog 2 (Drosophila), mRNA (cDNA clone MGC:48353 IMAGE:5274835), complete cds.AK022855 - Homo sapiens cDNA FLJ12793 fis, clone NT2RP2002033.JD369221 - Sequence 350245 from Patent EP1572962.JD384766 - Sequence 365790 from Patent EP1572962.AF510741 - Homo sapiens chromosome 1 unknown mRNA.JD311984 - Sequence 293008 from Patent EP1572962.JD308040 - Sequence 289064 from Patent EP1572962.JD435362 - Sequence 416386 from Patent EP1572962.JD435363 - Sequence 416387 from Patent EP1572962.JD308041 - Sequence 289065 from Patent EP1572962.JD218504 - Sequence 199528 from Patent EP1572962.JD522077 - Sequence 503101 from Patent EP1572962.JD514196 - Sequence 495220 from Patent EP1572962.JD514195 - Sequence 495219 from Patent EP1572962.JD514197 - Sequence 495221 from Patent EP1572962.AK093947 - Homo sapiens cDNA FLJ36628 fis, clone TRACH2017980.AL079275 - Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 566443.AK295116 - Homo sapiens cDNA FLJ56435 complete cds, highly similar to Homo sapiens angel homolog 2 (Drosophila) (ANGEL2), mRNA.AK299208 - Homo sapiens cDNA FLJ50627 complete cds, highly similar to Homo sapiens angel homolog 2 (Drosophila) (ANGEL2), mRNA.AK310946 - Homo sapiens cDNA, FLJ17988.AK294479 - Homo sapiens cDNA FLJ50488 complete cds, highly similar to Homo sapiens angel homolog 2 (Drosophila) (ANGEL2), mRNA.AK299365 - Homo sapiens cDNA FLJ50631 complete cds, highly similar to Homo sapiens angel homolog 2 (Drosophila) (ANGEL2), mRNA.CU690426 - Synthetic construct Homo sapiens gateway clone IMAGE:100020832 5' read ANGEL2 mRNA.KJ903551 - Synthetic construct Homo sapiens clone ccsbBroadEn_12945 ANGEL2 gene, encodes complete protein.AK311276 - Homo sapiens cDNA, FLJ18318.BC016966 - Homo sapiens angel homolog 2 (Drosophila), mRNA (cDNA clone IMAGE:4403747), complete cds.AY468376 - Homo sapiens LOC90806-like mRNA, complete sequence.KJ903550 - Synthetic construct Homo sapiens clone ccsbBroadEn_12944 ANGEL2 gene, encodes complete protein.JD026137 - Sequence 7161 from Patent EP1572962.JD034817 - Sequence 15841 from Patent EP1572962.
Other Names for This Gene
Alternate Gene Symbols: AK299208, F5H476, F5H476_HUMANUCSC ID: uc010pto.2RefSeq Accession: NM_144567
Protein: F5H476
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
AK299208.1
exon count:
9 CDS single in 3' UTR:
no
RNA size:
1944
ORF size:
1257 CDS single in intron:
no
Alignment % ID:
99.85
txCdsPredict score:
2426.00 frame shift in genome:
no
% Coverage:
99.95
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
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Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.