Human Gene DNAJC9 (uc010qkg.2)
  Description: Homo sapiens DnaJ (Hsp40) homolog, subfamily C, member 9 (DNAJC9), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr10:75,002,582-75,008,620 Size: 6,039 Total Exon Count: 5 Strand: -
Coding Region
   Position: hg19 chr10:75,003,158-75,006,947 Size: 3,790 Coding Exon Count: 5 

Page IndexSequence and LinksUniProtKB CommentsPrimersGenetic AssociationsMalaCards
CTDGene AllelesRNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein Structure
Other SpeciesGO AnnotationsmRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr10:75,002,582-75,008,620)mRNA (may differ from genome)Protein (260 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
GeneNetworkH-INVHGNCLynxMalacardsMGI
neXtProtOMIMPubMedTreefamUniProtKBWikipedia
BioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: DNJC9_HUMAN
DESCRIPTION: RecName: Full=DnaJ homolog subfamily C member 9; AltName: Full=DnaJ protein SB73;
SIMILARITY: Contains 1 J domain.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database (archive): DNAJC9
CDC HuGE Published Literature: DNAJC9

-  MalaCards Disease Associations
  MalaCards Gene Search: DNAJC9
Diseases sorted by gene-association score: recurrent corneal erosion (8), cervical squamous cell carcinoma (7), corneal degeneration (7)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 27.61 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 585.67 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -524.371673-0.313 Picture PostScript Text
3' UTR -156.64576-0.272 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR001623 - DnaJ_N
IPR018253 - Heat_shock_DnaJ_CS
IPR003095 - Hsp_DnaJ

Pfam Domains:
PF00226 - DnaJ domain

SCOP Domains:
46565 - Chaperone J-domain

ModBase Predicted Comparative 3D Structure on Q8WXX5
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserGenome BrowserGenome BrowserGenome BrowserNo ortholog
Gene DetailsGene Details Gene DetailsGene Details 
Gene SorterGene Sorter Gene SorterGene Sorter 
 RGDEnsemblFlyBaseWormBase 
 Protein SequenceProtein SequenceProtein SequenceProtein Sequence 
 AlignmentAlignmentAlignmentAlignment 

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0031072 heat shock protein binding

Biological Process:
GO:0032781 positive regulation of ATPase activity
GO:0035176 social behavior

Cellular Component:
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0016020 membrane


-  Descriptions from all associated GenBank mRNAs
  LF209951 - JP 2014500723-A/17454: Polycomb-Associated Non-Coding RNAs.
AK074420 - Homo sapiens cDNA FLJ23840 fis, clone KAT02642.
AF327347 - Homo sapiens DnaJ protein SB73 mRNA, complete cds.
AK094162 - Homo sapiens cDNA FLJ36843 fis, clone ASTRO2012552, highly similar to DnaJ homolog subfamily C member 9.
JD163287 - Sequence 144311 from Patent EP1572962.
JD371154 - Sequence 352178 from Patent EP1572962.
JD164091 - Sequence 145115 from Patent EP1572962.
JD481815 - Sequence 462839 from Patent EP1572962.
JD378872 - Sequence 359896 from Patent EP1572962.
JD053355 - Sequence 34379 from Patent EP1572962.
JD566563 - Sequence 547587 from Patent EP1572962.
BC136507 - Homo sapiens DnaJ (Hsp40) homolog, subfamily C, member 9, mRNA (cDNA clone MGC:168119 IMAGE:9020496), complete cds.
LF333143 - JP 2014500723-A/140646: Polycomb-Associated Non-Coding RNAs.
LF333145 - JP 2014500723-A/140648: Polycomb-Associated Non-Coding RNAs.
LF333147 - JP 2014500723-A/140650: Polycomb-Associated Non-Coding RNAs.
LF333149 - JP 2014500723-A/140652: Polycomb-Associated Non-Coding RNAs.
LF333150 - JP 2014500723-A/140653: Polycomb-Associated Non-Coding RNAs.
AK303204 - Homo sapiens cDNA FLJ58442 complete cds, highly similar to 28S ribosomal protein S16, mitochondrial precursor (S16mt).
LF333152 - JP 2014500723-A/140655: Polycomb-Associated Non-Coding RNAs.
AK025715 - Homo sapiens cDNA: FLJ22062 fis, clone HEP10276, highly similar to AF151890 Homo sapiens CGI-132 protein mRNA.
AK098291 - Homo sapiens cDNA FLJ40972 fis, clone UTERU2012938.
MA445528 - JP 2018138019-A/17454: Polycomb-Associated Non-Coding RNAs.
MA568720 - JP 2018138019-A/140646: Polycomb-Associated Non-Coding RNAs.
MA568722 - JP 2018138019-A/140648: Polycomb-Associated Non-Coding RNAs.
MA568724 - JP 2018138019-A/140650: Polycomb-Associated Non-Coding RNAs.
MA568726 - JP 2018138019-A/140652: Polycomb-Associated Non-Coding RNAs.
MA568727 - JP 2018138019-A/140653: Polycomb-Associated Non-Coding RNAs.
MA568729 - JP 2018138019-A/140655: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: AK094162, DNJC9_HUMAN, NM_015190, NP_056005, Q8WXX5
UCSC ID: uc010qkg.2
RefSeq Accession: NM_015190
Protein: Q8WXX5 (aka DNJC9_HUMAN or DJC9_HUMAN)
CCDS: CCDS7322.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: AK094162.1
exon count: 5CDS single in 3' UTR: no RNA size: 3024
ORF size: 783CDS single in intron: no Alignment % ID: 99.97
txCdsPredict score: 1006.50frame shift in genome: no % Coverage: 100.00
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 1358# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.