Human Gene ANKRD13A (uc010sxw.2)
Description: Homo sapiens ankyrin repeat domain 13A (ANKRD13A), mRNA.
Transcript (Including UTRs)
Position: hg19 chr12:110,437,235-110,477,235 Size: 40,001 Total Exon Count: 15 Strand: +
Coding Region
Position: hg19 chr12:110,437,494-110,475,359 Size: 37,866 Coding Exon Count: 15
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Primer design for this transcript
Genetic Association Studies of Complex Diseases and Disorders
Genetic Association Database (archive): ANKRD13A
CDC HuGE Published Literature: ANKRD13A
Positive Disease Associations: Body Weights and Measures
Related Studies: Body Weights and Measures Caroline S Fox et al. BMC medical genetics 2007, Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project., BMC medical genetics.
[PubMed 17903300 ]
Adiposity traits are associated with SNPs on the Affymetrix 100K SNP GeneChip. Replication of these initial findings is necessary. These data will serve as a resource for replication as more genes become identified with BMI and WC.
MalaCards Disease Associations
Comparative Toxicogenomics Database (CTD)
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR021832 - ANKRD13
IPR002110 - Ankyrin_rpt
IPR020683 - Ankyrin_rpt-contain_dom
IPR003903 - Ubiquitin-int_motif
Pfam Domains: PF00023 - Ankyrin repeat
PF02809 - Ubiquitin interaction motif
PF11904 - GPCR-chaperone
PF12796 - Ankyrin repeats (3 copies)
PF13606 - Ankyrin repeat
PF13637 - Ankyrin repeats (many copies)
PF13857 - Ankyrin repeats (many copies)
SCOP Domains: 48403 - Ankyrin repeat
ModBase Predicted Comparative 3D Structure on B4DYP5
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Descriptions from all associated GenBank mRNAs
AK308923 - Homo sapiens cDNA, FLJ98964.BC057817 - Homo sapiens ankyrin repeat domain 13A, mRNA (cDNA clone IMAGE:30346590), with apparent retained intron.AK025261 - Homo sapiens cDNA: FLJ21608 fis, clone COL07313, highly similar to AF155103 Homo sapiens NY-REN-25 antigen mRNA.AF064604 - Homo sapiens KE03 protein mRNA, partial cds.AK302535 - Homo sapiens cDNA FLJ54725 complete cds, highly similar to Ankyrin repeat domain-containing protein 13.BC032833 - Homo sapiens ankyrin repeat domain 13A, mRNA (cDNA clone MGC:26764 IMAGE:4830174), complete cds.JD151814 - Sequence 132838 from Patent EP1572962.JD106759 - Sequence 87783 from Patent EP1572962.CU691256 - Synthetic construct Homo sapiens gateway clone IMAGE:100022814 5' read ANKRD13A mRNA.KJ903525 - Synthetic construct Homo sapiens clone ccsbBroadEn_12919 ANKRD13A gene, encodes complete protein.AY364251 - Homo sapiens clone peg2085 NY-REN-25 antigen (ANKRD13) mRNA, complete cds.AK293232 - Homo sapiens cDNA FLJ53297 complete cds, highly similar to Ankyrin repeat domain-containing protein 13.AF155103 - Homo sapiens NY-REN-25 antigen mRNA, partial cds.AK130522 - Homo sapiens cDNA FLJ27012 fis, clone SLV05358.AK022658 - Homo sapiens cDNA FLJ12596 fis, clone NT2RM4001347, highly similar to Ankyrin repeat domain-containing protein 13.AK095130 - Homo sapiens cDNA FLJ37811 fis, clone BRSSN2001869, moderately similar to Ankyrin repeat domain-containing protein 13.JD503761 - Sequence 484785 from Patent EP1572962.JD307338 - Sequence 288362 from Patent EP1572962.JD323661 - Sequence 304685 from Patent EP1572962.JD065983 - Sequence 47007 from Patent EP1572962.JD155729 - Sequence 136753 from Patent EP1572962.JD074356 - Sequence 55380 from Patent EP1572962.JD191746 - Sequence 172770 from Patent EP1572962.JD511034 - Sequence 492058 from Patent EP1572962.JD535183 - Sequence 516207 from Patent EP1572962.JD216142 - Sequence 197166 from Patent EP1572962.JD471322 - Sequence 452346 from Patent EP1572962.JD363962 - Sequence 344986 from Patent EP1572962.JD509746 - Sequence 490770 from Patent EP1572962.JD438742 - Sequence 419766 from Patent EP1572962.DQ595076 - Homo sapiens piRNA piR-61188, complete sequence.JD137329 - Sequence 118353 from Patent EP1572962.JD356827 - Sequence 337851 from Patent EP1572962.JD242177 - Sequence 223201 from Patent EP1572962.JD203171 - Sequence 184195 from Patent EP1572962.JD289533 - Sequence 270557 from Patent EP1572962.JD245986 - Sequence 227010 from Patent EP1572962.JD504984 - Sequence 486008 from Patent EP1572962.JD185627 - Sequence 166651 from Patent EP1572962.JD318282 - Sequence 299306 from Patent EP1572962.JD384487 - Sequence 365511 from Patent EP1572962.JD516178 - Sequence 497202 from Patent EP1572962.JD500223 - Sequence 481247 from Patent EP1572962.JD303118 - Sequence 284142 from Patent EP1572962.JD260628 - Sequence 241652 from Patent EP1572962.DQ570877 - Homo sapiens piRNA piR-30989, complete sequence.JD549302 - Sequence 530326 from Patent EP1572962.JD109406 - Sequence 90430 from Patent EP1572962.
Other Names for This Gene
Alternate Gene Symbols: AK302535, B4DYP5, B4DYP5_HUMAN, NM_033121, NP_149112UCSC ID: uc010sxw.2RefSeq Accession: NM_033121
Protein: B4DYP5
CCDS: CCDS9140.1
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
AK302535.1
exon count:
15 CDS single in 3' UTR:
no
RNA size:
1905
ORF size:
1770 CDS single in intron:
no
Alignment % ID:
99.95
txCdsPredict score:
3672.00 frame shift in genome:
no
% Coverage:
100.00
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
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Methods, Credits, and Use Restrictions
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