ID:E7EUK6_HUMAN DESCRIPTION: SubName: Full=Hepatic triacylglycerol lipase; SIMILARITY: Belongs to the AB hydrolase superfamily. Lipase family. CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
Amyotrophic lateral sclerosis van Es ,et al. 2007, Genetic variation in DPP6 is associated with susceptibility to amyotrophic lateral sclerosis, .
[PubMed 18084291]
Amyotrophic Lateral Sclerosis Michael A van Es et al. Nature genetics 2008, Genetic variation in DPP6 is associated with susceptibility to amyotrophic lateral sclerosis., Nature genetics.
[PubMed 18084291]
atherosclerosis, coronary Baroni, M. G. et al. 2003, Genetic study of common variants at the Apo E, Apo AI, Apo CIII, Apo B, lipoprotein lipase (LPL) and hepatic lipase (LIPC) genes and coronary artery disease (CAD): variation in LIPC gene associateswith clinical outcomes in patients with established CAD., BMC medical genetics [electronic resource]. 2003 Sep;4:8.
[PubMed 12964943]
variation in LIPC (hepatic lipase) gene associates with clinical outcomes in Italian patients with established CAD. Further studies on the LIPC gene in CAD patients are warranted, in particular looking at the possible influences on clinical outcomes.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on E7EUK6
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.