Human Gene ZNF213 (uc010uwt.3)
Description: Homo sapiens zinc finger protein 213 (ZNF213), transcript variant 2, mRNA.
RefSeq Summary (NM_001134655): C2H2 zinc finger proteins, such as ZNF213, have bipartite structures in which one domain binds DNA or RNA and the other modulates target gene expression.[supplied by OMIM, Apr 2004].
Transcript (Including UTRs)
Position: hg19 chr16:3,187,167-3,192,805 Size: 5,639 Total Exon Count: 4 Strand: +
Coding Region
Position: hg19 chr16:3,188,420-3,191,348 Size: 2,929 Coding Exon Count: 3
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Primer design for this transcript
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR001909 - Krueppel-associated_box
IPR007087 - Znf_C2H2
IPR015880 - Znf_C2H2-like
IPR013087 - Znf_C2H2/integrase_DNA-bd
Pfam Domains: PF00096 - Zinc finger, C2H2 type
PF01352 - KRAB box
PF13465 - Zinc-finger double domain
PF13912 - C2H2-type zinc finger
SCOP Domains: 48695 - Multiheme cytochromes
109640 - KRAB domain (Kruppel-associated box, Pfam 01352)
57667 - C2H2 and C2HC zinc fingers
ModBase Predicted Comparative 3D Structure on B4DMG6
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse Rat Zebrafish D. melanogaster C. elegans S. cerevisiae
No ortholog No ortholog No ortholog No ortholog No ortholog No ortholog
Gene Details
Gene Sorter
Descriptions from all associated GenBank mRNAs
AF017433 - Homo sapiens putative transcription factor CR53 (CR53) mRNA, partial cds.BC007287 - Homo sapiens zinc finger protein 213, mRNA (cDNA clone MGC:15660 IMAGE:3347511), complete cds.BC116445 - Homo sapiens cDNA clone IMAGE:4914721, with apparent retained intron.AK291789 - Homo sapiens cDNA FLJ77635 complete cds, highly similar to Homo sapiens zinc finger protein 213, mRNA.AK055337 - Homo sapiens cDNA FLJ30775 fis, clone FEBRA2000787, highly similar to Homo sapiens putative transcription factor CR53 (CR53) mRNA.AK289834 - Homo sapiens cDNA FLJ75075 complete cds, highly similar to Homo sapiens zinc finger protein 213 (ZNF213), mRNA.JD504628 - Sequence 485652 from Patent EP1572962.JD332838 - Sequence 313862 from Patent EP1572962.JD291048 - Sequence 272072 from Patent EP1572962.CU675597 - Synthetic construct Homo sapiens gateway clone IMAGE:100020697 5' read ZNF213 mRNA.AB464383 - Synthetic construct DNA, clone: pF1KB7791, Homo sapiens ZNF213 gene for zinc finger protein 213, without stop codon, in Flexi system.KU178402 - Homo sapiens zinc finger protein 213 isoform 1 (ZNF213) mRNA, partial cds.KU178403 - Homo sapiens zinc finger protein 213 isoform 2 (ZNF213) mRNA, partial cds, alternatively spliced.JF432377 - Synthetic construct Homo sapiens clone IMAGE:100073574 zinc finger protein 213 (ZNF213) gene, encodes complete protein.KJ892425 - Synthetic construct Homo sapiens clone ccsbBroadEn_01819 ZNF213 gene, encodes complete protein.AK297454 - Homo sapiens cDNA FLJ53809 complete cds, highly similar to Zinc finger protein 213.BC007598 - Homo sapiens zinc finger protein 213, mRNA (cDNA clone IMAGE:3346912), partial cds.JD333076 - Sequence 314100 from Patent EP1572962.JD466259 - Sequence 447283 from Patent EP1572962.JD116581 - Sequence 97605 from Patent EP1572962.JD521477 - Sequence 502501 from Patent EP1572962.JD397946 - Sequence 378970 from Patent EP1572962.JD389650 - Sequence 370674 from Patent EP1572962.JD508555 - Sequence 489579 from Patent EP1572962.JD361750 - Sequence 342774 from Patent EP1572962.JD203925 - Sequence 184949 from Patent EP1572962.BC080572 - Homo sapiens cDNA clone IMAGE:6568471.BC012772 - Homo sapiens zinc finger protein 213, mRNA (cDNA clone IMAGE:3835682), partial cds.JD325722 - Sequence 306746 from Patent EP1572962.JD341698 - Sequence 322722 from Patent EP1572962.JD400502 - Sequence 381526 from Patent EP1572962.JD108743 - Sequence 89767 from Patent EP1572962.JD478230 - Sequence 459254 from Patent EP1572962.JD534469 - Sequence 515493 from Patent EP1572962.JD125239 - Sequence 106263 from Patent EP1572962.JD392920 - Sequence 373944 from Patent EP1572962.JD142251 - Sequence 123275 from Patent EP1572962.JD058710 - Sequence 39734 from Patent EP1572962.JD055068 - Sequence 36092 from Patent EP1572962.JD058624 - Sequence 39648 from Patent EP1572962.JD392920 - Sequence 373944 from Patent EP1572962.JD400029 - Sequence 381053 from Patent EP1572962.JD427295 - Sequence 408319 from Patent EP1572962.JD474073 - Sequence 455097 from Patent EP1572962.JD411453 - Sequence 392477 from Patent EP1572962.JD493358 - Sequence 474382 from Patent EP1572962.JD474074 - Sequence 455098 from Patent EP1572962.JD320107 - Sequence 301131 from Patent EP1572962.
Other Names for This Gene
Alternate Gene Symbols: AK297454, B4DMG6, B4DMG6_HUMAN, uc010uwt.2UCSC ID: uc010uwt.3RefSeq Accession: NM_001134655
Protein: B4DMG6
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
AK297454.1
exon count:
4 CDS single in 3' UTR:
no
RNA size:
1313
ORF size:
906 CDS single in intron:
no
Alignment % ID:
99.92
txCdsPredict score:
1591.00 frame shift in genome:
no
% Coverage:
100.00
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
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Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.