Human Gene TLCD1 (uc010waw.2)
Description: Homo sapiens TLC domain containing 1 (TLCD1), transcript variant 2, mRNA.
Transcript (Including UTRs)
Position: hg19 chr17:27,051,366-27,053,949 Size: 2,584 Total Exon Count: 4 Strand: -
Coding Region
Position: hg19 chr17:27,051,528-27,053,826 Size: 2,299 Coding Exon Count: 4
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: A8MYP9_HUMAN
DESCRIPTION: SubName: Full=TLC domain containing 1, isoform CRA_b; SubName: Full=TLC domain-containing protein 1;
SIMILARITY: Contains 1 TLC (TRAM/LAG1/CLN8) domain.
Primer design for this transcript
Comparative Toxicogenomics Database (CTD)
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR006634 - TLC-dom
Pfam Domains: PF03798 - TLC domain
ModBase Predicted Comparative 3D Structure on A8MYP9
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse Rat Zebrafish D. melanogaster C. elegans S. cerevisiae
No ortholog No ortholog No ortholog No ortholog No ortholog No ortholog
Gene Details
Gene Sorter
Descriptions from all associated GenBank mRNAs
LF209209 - JP 2014500723-A/16712: Polycomb-Associated Non-Coding RNAs.BC014072 - Homo sapiens TLC domain containing 1, mRNA (cDNA clone MGC:20499 IMAGE:3957355), complete cds.JD105196 - Sequence 86220 from Patent EP1572962.JD179432 - Sequence 160456 from Patent EP1572962.JD071208 - Sequence 52232 from Patent EP1572962.LF326823 - JP 2014500723-A/134326: Polycomb-Associated Non-Coding RNAs.JD189938 - Sequence 170962 from Patent EP1572962.EU831756 - Synthetic construct Homo sapiens clone HAIB:100066785; DKFZo008A1221 TLC domain containing 1 protein (TLCD1) gene, encodes complete protein.JF432650 - Synthetic construct Homo sapiens clone IMAGE:100073887 TLC domain containing 1 (TLCD1) gene, encodes complete protein.EU831834 - Synthetic construct Homo sapiens clone HAIB:100066863; DKFZo004A1222 TLC domain containing 1 protein (TLCD1) gene, encodes complete protein.KJ895309 - Synthetic construct Homo sapiens clone ccsbBroadEn_04703 TLCD1 gene, encodes complete protein.LF326822 - JP 2014500723-A/134325: Polycomb-Associated Non-Coding RNAs.LF326821 - JP 2014500723-A/134324: Polycomb-Associated Non-Coding RNAs.MA562400 - JP 2018138019-A/134326: Polycomb-Associated Non-Coding RNAs.MA562399 - JP 2018138019-A/134325: Polycomb-Associated Non-Coding RNAs.MA562398 - JP 2018138019-A/134324: Polycomb-Associated Non-Coding RNAs.MA444786 - JP 2018138019-A/16712: Polycomb-Associated Non-Coding RNAs.
Other Names for This Gene
Alternate Gene Symbols: A8MYP9, A8MYP9_HUMAN, hCG_31813, NM_001160407, NP_001153879UCSC ID: uc010waw.2RefSeq Accession: NM_001160407
Protein: A8MYP9
CCDS: CCDS54102.1
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
NM_001160407.1
exon count:
4 CDS single in 3' UTR:
no
RNA size:
904
ORF size:
603 CDS single in intron:
no
Alignment % ID:
100.00
txCdsPredict score:
1406.00 frame shift in genome:
no
% Coverage:
98.23
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
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Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.