Human Gene CD300LG (uc010wil.2)
  Description: Homo sapiens CD300 molecule-like family member g (CD300LG), transcript variant 3, mRNA.
RefSeq Summary (NM_001168323): Members of the CD300 (see MIM 606786)-like (CD300L) family, such as CD300LG, are widely expressed on hematopoietic cells. All CD300L proteins are type I cell surface glycoproteins that contain a single immunoglobulin (Ig) V-like domain (Takatsu et al., 2006 [PubMed 16876123]).[supplied by OMIM, Mar 2008].
Transcript (Including UTRs)
   Position: hg19 chr17:41,924,516-41,935,602 Size: 11,087 Total Exon Count: 6 Strand: +
Coding Region
   Position: hg19 chr17:41,924,585-41,935,196 Size: 10,612 Coding Exon Count: 6 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther SpeciesmRNA Descriptions
Other NamesModel InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr17:41,924,516-41,935,602)mRNA (may differ from genome)Protein (273 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaAlphaFoldBioGPS
EnsemblEntrez GeneExonPrimerGeneCardsH-INVHGNC
LynxMGIOMIMPubMedTreefamUniProtKB
BioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: F8W9M3_HUMAN
DESCRIPTION: SubName: Full=CMRF35-like molecule 9;
CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 41.08 RPKM in Adipose - Visceral (Omentum)
Total median expression: 163.29 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -19.6069-0.284 Picture PostScript Text
3' UTR -164.20406-0.404 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR007110 - Ig-like
IPR013783 - Ig-like_fold
IPR003599 - Ig_sub
IPR013106 - Ig_V-set

Pfam Domains:
PF00047 - Immunoglobulin domain
PF07686 - Immunoglobulin V-set domain

SCOP Domains:
48726 - Immunoglobulin

ModBase Predicted Comparative 3D Structure on F8W9M3
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
      
      
      

-  Descriptions from all associated GenBank mRNAs
  AK298112 - Homo sapiens cDNA FLJ52007 complete cds, highly similar to Homo sapiens CD300 antigen like family member G (CD300LG), mRNA.
AK309938 - Homo sapiens cDNA, FLJ99979.
AF427619 - Homo sapiens TREM4 alpha mRNA, complete cds.
AF427620 - Homo sapiens TREM4 beta mRNA, complete cds.
JD058070 - Sequence 39094 from Patent EP1572962.
BC025395 - Homo sapiens CD300 molecule-like family member g, mRNA (cDNA clone MGC:26887 IMAGE:4827737), complete cds.
AY358364 - Homo sapiens clone DNA44196 RLLV422 (UNQ422) mRNA, complete cds.
CU692992 - Synthetic construct Homo sapiens gateway clone IMAGE:100018120 5' read CD300LG mRNA.
HQ447197 - Synthetic construct Homo sapiens clone IMAGE:100070494; CCSB001516_01 CD300 molecule-like family member g (CD300LG) gene, encodes complete protein.
KJ900244 - Synthetic construct Homo sapiens clone ccsbBroadEn_09638 CD300LG gene, encodes complete protein.

-  Other Names for This Gene
  Alternate Gene Symbols: F8W9M3, F8W9M3_HUMAN, NM_001168323, NP_001161795
UCSC ID: uc010wil.2
RefSeq Accession: NM_001168323
Protein: F8W9M3 CCDS: CCDS54132.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_001168323.1
exon count: 6CDS single in 3' UTR: no RNA size: 1297
ORF size: 822CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 1828.00frame shift in genome: no % Coverage: 100.00
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.