ID:E7EUF8_HUMAN DESCRIPTION: SubName: Full=Band 4.1-like protein 3; CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
Amyotrophic Lateral Sclerosis Simon Cronin et al. Human molecular genetics 2008, A genome-wide association study of sporadic ALS in a homogenous Irish population., Human molecular genetics.
[PubMed 18057069]
Body Weights and Measures Caroline S Fox et al. BMC medical genetics 2007, Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project., BMC medical genetics.
[PubMed 17903300]
Adiposity traits are associated with SNPs on the Affymetrix 100K SNP GeneChip. Replication of these initial findings is necessary. These data will serve as a resource for replication as more genes become identified with BMI and WC.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF04382 - SAB domain PF05902 - 4.1 protein C-terminal domain (CTD)
ModBase Predicted Comparative 3D Structure on E7EUF8
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
AB023204 - Homo sapiens KIAA0987 mRNA for KIAA0987 protein. AK128531 - Homo sapiens cDNA FLJ46689 fis, clone TRACH3012106, highly similar to Band 4.1-like protein 3. BC008377 - Homo sapiens erythrocyte membrane protein band 4.1-like 3, mRNA (cDNA clone IMAGE:4044866), partial cds. AF069072 - Homo sapiens putative lung tumor suppressor (DAL1) mRNA, complete cds. AK297406 - Homo sapiens cDNA FLJ58675 complete cds, highly similar to Band 4.1-like protein 3. BC006141 - Homo sapiens erythrocyte membrane protein band 4.1-like 3, mRNA (cDNA clone MGC:13087 IMAGE:3936453), complete cds. AK292583 - Homo sapiens cDNA FLJ77757 complete cds. AK090875 - Homo sapiens cDNA FLJ33556 fis, clone BRAMY2009394. AK094952 - Homo sapiens cDNA FLJ37633 fis, clone BRCOC2017652, highly similar to Band 4.1-like protein 3. AL832598 - Homo sapiens mRNA; cDNA DKFZp451B0417 (from clone DKFZp451B0417). AF515797 - Homo sapiens HSF protein (EPB41L3) mRNA, partial cds. JD374782 - Sequence 355806 from Patent EP1572962. JD490875 - Sequence 471899 from Patent EP1572962. AK294690 - Homo sapiens cDNA FLJ53317 complete cds, highly similar to Band 4.1-like protein 3. AK295453 - Homo sapiens cDNA FLJ59529 complete cds, highly similar to Band 4.1-like protein 3. AK303679 - Homo sapiens cDNA FLJ56196 complete cds, highly similar to Band 4.1-like protein 3. JD065487 - Sequence 46511 from Patent EP1572962. AK294610 - Homo sapiens cDNA FLJ54069 complete cds, highly similar to Band 4.1-like protein 3. KJ902290 - Synthetic construct Homo sapiens clone ccsbBroadEn_11684 EPB41L3 gene, encodes complete protein. AB385414 - Synthetic construct DNA, clone: pF1KA0987, Homo sapiens EPB41L3 gene for band 4.1-like protein 3, complete cds, without stop codon, in Flexi system. JD084243 - Sequence 65267 from Patent EP1572962. AK307751 - Homo sapiens cDNA, FLJ97699. JD115594 - Sequence 96618 from Patent EP1572962. JD040786 - Sequence 21810 from Patent EP1572962. JD353396 - Sequence 334420 from Patent EP1572962. JD052483 - Sequence 33507 from Patent EP1572962. JD047309 - Sequence 28333 from Patent EP1572962. JD513130 - Sequence 494154 from Patent EP1572962. JD036775 - Sequence 17799 from Patent EP1572962. JD081266 - Sequence 62290 from Patent EP1572962. JD211803 - Sequence 192827 from Patent EP1572962. JD217834 - Sequence 198858 from Patent EP1572962. JD485668 - Sequence 466692 from Patent EP1572962. JD077539 - Sequence 58563 from Patent EP1572962. JD473050 - Sequence 454074 from Patent EP1572962. JD106993 - Sequence 88017 from Patent EP1572962. JD535263 - Sequence 516287 from Patent EP1572962. AK314438 - Homo sapiens cDNA, FLJ95236, highly similar to Homo sapiens differentially expressed in adenocarcinoma of the lung, mRNA.
Biochemical and Signaling Pathways
KEGG - Kyoto Encyclopedia of Genes and Genomes hsa04530 - Tight junction