Human Gene TASP1 (uc010zrj.1)
  Description: Homo sapiens taspase, threonine aspartase, 1 (TASP1), mRNA.
RefSeq Summary (NM_017714): This gene encodes an endopeptidase that cleaves specific substrates following aspartate residues. The encoded protein undergoes posttranslational autoproteolytic processing to generate alpha and beta subunits, which reassemble into the active alpha2-beta2 heterotetramer. It is required to cleave MLL, a protein required for the maintenance of HOX gene expression, and TFIIA, a basal transcription factor. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].
Transcript (Including UTRs)
   Position: hg19 chr20:13,463,874-13,619,583 Size: 155,710 Total Exon Count: 11 Strand: -


Page IndexSequence and LinksPrimersCTDRNA-Seq ExpressionMicroarray Expression
Other SpeciesmRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr20:13,463,874-13,619,583)mRNA (may differ from genome)No protein
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
BioGPSEnsemblExonPrimerGeneNetworkH-INVHGNC
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-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 14.84 RPKM in Artery - Tibial
Total median expression: 176.49 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  AK299940 - Homo sapiens cDNA FLJ50393 complete cds, moderately similar to Threonine aspartase 1 (EC 3.4.25.-).
AK000219 - Homo sapiens cDNA FLJ20212 fis, clone COLF1860.
AK025671 - Homo sapiens cDNA: FLJ22018 fis, clone HEP07914.
BC025266 - Homo sapiens taspase, threonine aspartase, 1, mRNA (cDNA clone MGC:39159 IMAGE:3929609), complete cds.
AK304488 - Homo sapiens cDNA FLJ52055 complete cds, moderately similar to Threonine aspartase 1 (EC 3.4.25.-).
AK316311 - Homo sapiens cDNA, FLJ79210 complete cds, moderately similar to Threonine aspartase 1 (EC 3.4.25.-).

-  Other Names for This Gene
  Alternate Gene Symbols: AK304488
UCSC ID: uc010zrj.1
RefSeq Accession: NM_017714

-  Gene Model Information
 
category: nearCoding nonsense-mediated-decay: no RNA accession: AK304488.1
exon count: 11CDS single in 3' UTR: no RNA size: 1244
ORF size: 0CDS single in intron: no Alignment % ID: 99.92
txCdsPredict score: 535.00frame shift in genome: no % Coverage: 100.00
has start codon: no stop codon in genome: no # of Alignments: 1
has end codon: no retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.