Human Gene YTHDF1 (uc011aaq.2)
Description: Homo sapiens YTH domain family, member 1 (YTHDF1), mRNA.
Transcript (Including UTRs)
Position: hg19 chr20:61,826,782-61,839,970 Size: 13,189 Total Exon Count: 3 Strand: -
Coding Region
Position: hg19 chr20:61,828,060-61,835,141 Size: 7,082 Coding Exon Count: 2
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: YTHD1_HUMAN
DESCRIPTION: RecName: Full=YTH domain family protein 1; AltName: Full=Dermatomyositis associated with cancer putative autoantigen 1; Short=DACA-1;
SIMILARITY: Contains 1 YTH domain.
Primer design for this transcript
Comparative Toxicogenomics Database (CTD)
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR007275 - YTH_domain
Pfam Domains: PF04146 - YT521-B-like domain
ModBase Predicted Comparative 3D Structure on Q9BYJ9
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
AK024546 - Homo sapiens cDNA: FLJ20893 fis, clone ADKA03459.AB055518 - Homo sapiens DACA-1 mRNA for dermatomyositis associated with cancer putative autoantigen-1, partial cds.AK000398 - Homo sapiens cDNA FLJ20391 fis, clone KAIA4640.BC016920 - Homo sapiens YTH domain family, member 1, mRNA (cDNA clone IMAGE:3853372), partial cds.BC003681 - Homo sapiens YTH domain family, member 1, mRNA (cDNA clone IMAGE:3453235), partial cds.BC050284 - Homo sapiens YTH domain family, member 1, mRNA (cDNA clone MGC:41808 IMAGE:5298438), complete cds.AK095795 - Homo sapiens cDNA FLJ38476 fis, clone FEBRA2022504, highly similar to YTH domain protein 1.AL834366 - Homo sapiens mRNA; cDNA DKFZp762G1112 (from clone DKFZp762G1112).JD566628 - Sequence 547652 from Patent EP1572962.JD514632 - Sequence 495656 from Patent EP1572962.JD333842 - Sequence 314866 from Patent EP1572962.JD341228 - Sequence 322252 from Patent EP1572962.JD227857 - Sequence 208881 from Patent EP1572962.JD079168 - Sequence 60192 from Patent EP1572962.JD471135 - Sequence 452159 from Patent EP1572962.JD182892 - Sequence 163916 from Patent EP1572962.JD295804 - Sequence 276828 from Patent EP1572962.BC025264 - Homo sapiens YTH domain family, member 1, mRNA (cDNA clone IMAGE:5087992), partial cds.AK300073 - Homo sapiens cDNA FLJ58619 complete cds, highly similar to YTH domain protein 1.JD256095 - Sequence 237119 from Patent EP1572962.JD377217 - Sequence 358241 from Patent EP1572962.KJ894085 - Synthetic construct Homo sapiens clone ccsbBroadEn_03479 YTHDF1 gene, encodes complete protein.
Other Names for This Gene
Alternate Gene Symbols: AK300073, C20orf21, NM_017798, NP_060268, Q8N3G5, Q8TBT1, Q96AN4, Q96S57, Q9BTI7, Q9BYJ9, Q9NX79, YTHD1_HUMANUCSC ID: uc011aaq.2RefSeq Accession: NM_017798
Protein: Q9BYJ9
(aka YTHD1_HUMAN or YTH1_HUMAN)
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
AK300073.1
exon count:
3 CDS single in 3' UTR:
no
RNA size:
1933
ORF size:
1530 CDS single in intron:
no
Alignment % ID:
99.90
txCdsPredict score:
3114.50 frame shift in genome:
no
% Coverage:
100.00
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
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Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.