Description: Homo sapiens chaperonin containing TCP1, subunit 8 (theta) (CCT8), mRNA. RefSeq Summary (NM_006585): This gene encodes the theta subunit of the CCT chaperonin, which is abundant in the eukaryotic cytosol and may be involved in the transport and assembly of newly synthesized proteins. Alternative splicing results in multiple transcript variants of this gene. A pseudogene related to this gene is located on chromosome 1. [provided by RefSeq, Sep 2013]. Transcript (Including UTRs) Position: hg19 chr21:30,428,648-30,445,672 Size: 17,025 Total Exon Count: 16 Strand: - Coding Region Position: hg19 chr21:30,428,796-30,444,275 Size: 15,480 Coding Exon Count: 15
ID:B4DEM7_HUMAN DESCRIPTION: SubName: Full=T-complex protein 1 subunit theta; SubName: Full=cDNA FLJ53379, highly similar to T-complex protein 1 subunit theta; SIMILARITY: Belongs to the TCP-1 chaperonin family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on B4DEM7
Front
Top
Side
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.