Description: Homo sapiens RAB, member of RAS oncogene family-like 2B (RABL2B), transcript variant 3, mRNA. RefSeq Summary (NM_001130919): The RABL2B protein is a member of the RAB gene family which belongs to the RAS GTPase superfamily. RABL2B is located within a subtelomeric region of 22q13.3. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]. Transcript (Including UTRs) Position: hg19 chr22:51,205,920-51,222,087 Size: 16,168 Total Exon Count: 9 Strand: - Coding Region Position: hg19 chr22:51,207,204-51,220,722 Size: 13,519 Coding Exon Count: 8
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
Pfam Domains: PF00025 - ADP-ribosylation factor family PF00071 - Ras family PF01926 - 50S ribosome-binding GTPase PF04670 - Gtr1/RagA G protein conserved region PF08477 - Ras of Complex, Roc, domain of DAPkinase
ModBase Predicted Comparative 3D Structure on Q9UNT1-2
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.