Human Gene SLC17A2 (uc011dkc.2)
  Description: Homo sapiens solute carrier family 17 (sodium phosphate), member 2 (SLC17A2), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr6:25,912,984-25,926,107 Size: 13,124 Total Exon Count: 10 Strand: -
Coding Region
   Position: hg19 chr6:25,913,672-25,926,024 Size: 12,353 Coding Exon Count: 10 

Page IndexSequence and LinksPrimersGenetic AssociationsCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther SpeciesmRNA Descriptions
Other NamesModel InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr6:25,912,984-25,926,107)mRNA (may differ from genome)Protein (398 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblExonPrimerGeneCardsGeneNetwork
HGNCLynxMGIPubMedTreefamUniProtKB
Wikipedia

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database (archive): SLC17A2
CDC HuGE Published Literature: SLC17A2

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 21.36 RPKM in Liver
Total median expression: 21.68 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -16.2083-0.195 Picture PostScript Text
3' UTR -200.49688-0.291 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  Pfam Domains:
PF07690 - Major Facilitator Superfamily

SCOP Domains:
103473 - MFS general substrate transporter

ModBase Predicted Comparative 3D Structure on O00624-2
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
      
      
      

-  Descriptions from all associated GenBank mRNAs
  U90544 - Human sodium phosphate transporter (NPT3) mRNA, complete cds.
JD244939 - Sequence 225963 from Patent EP1572962.
JD350043 - Sequence 331067 from Patent EP1572962.
JD508138 - Sequence 489162 from Patent EP1572962.
BC143323 - Homo sapiens cDNA clone IMAGE:9051828.
BC104822 - Homo sapiens solute carrier family 17 (sodium phosphate), member 2, mRNA (cDNA clone MGC:132482 IMAGE:8143825), complete cds.
BC112033 - Homo sapiens solute carrier family 17 (sodium phosphate), member 2, mRNA (cDNA clone MGC:138238 IMAGE:8327501), complete cds.
BC143317 - Homo sapiens cDNA clone IMAGE:9051822, with apparent retained intron.
KJ892975 - Synthetic construct Homo sapiens clone ccsbBroadEn_02369 SLC17A2 gene, encodes complete protein.
Y10505 - H.sapiens mRNA for CD104 protein.

-  Other Names for This Gene
  Alternate Gene Symbols: BC143317, NPT3, O00624-2
UCSC ID: uc011dkc.2
RefSeq Accession: NM_005835
Protein: O00624-2, splice isoform of O00624

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: BC143317.1
exon count: 10CDS single in 3' UTR: no RNA size: 1464
ORF size: 1197CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 2325.00frame shift in genome: no % Coverage: 100.00
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.