Description: Homo sapiens mitochondrial carrier 1 (MTCH1), nuclear gene encoding mitochondrial protein, transcript variant 1, mRNA. RefSeq Summary (NM_014341): This gene encodes a member of the mitochondrial carrier family. The encoded protein is localized to the mitochondrion inner membrane and induces apoptosis independent of the proapoptotic proteins Bax and Bak. Pseudogenes on chromosomes 6 and 11 have been identified for this gene. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Oct 2012]. Transcript (Including UTRs) Position: hg19 chr6:36,937,502-36,954,327 Size: 16,826 Total Exon Count: 10 Strand: - Coding Region Position: hg19 chr6:36,937,629-36,946,289 Size: 8,661 Coding Exon Count: 9
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on B4E0C5
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
