Human Gene TEX15 (uc011lbc.2)
  Description: Homo sapiens testis expressed 15, mRNA (cDNA clone IMAGE:8860305), partial cds.
Transcript (Including UTRs)
   Position: hg19 chr8:30,706,243-30,746,222 Size: 39,980 Total Exon Count: 7 Strand: -
Coding Region
   Position: hg19 chr8:30,706,243-30,746,154 Size: 39,912 Coding Exon Count: 7 

Page IndexSequence and LinksPrimersGenetic AssociationsMalaCardsCTD
Gene AllelesRNA-Seq ExpressionMicroarray ExpressionRNA StructureOther SpeciesmRNA Descriptions
Other NamesModel InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr8:30,706,243-30,746,222)mRNA (may differ from genome)Protein (484 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaEnsembl
ExonPrimerGeneCardsHGNCLynxMalacardsMGI
PubMed

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database (archive): TEX15
CDC HuGE Published Literature: TEX15
Positive Disease Associations: Body Height , Body Weights and Measures
Related Studies:
  1. Body Height
    Caroline S Fox et al. BMC medical genetics 2007, Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project., BMC medical genetics. [PubMed 17903300]
    Adiposity traits are associated with SNPs on the Affymetrix 100K SNP GeneChip. Replication of these initial findings is necessary. These data will serve as a resource for replication as more genes become identified with BMI and WC.
  2. Body Weights and Measures
    Caroline S Fox et al. BMC medical genetics 2007, Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project., BMC medical genetics. [PubMed 17903300]
    Adiposity traits are associated with SNPs on the Affymetrix 100K SNP GeneChip. Replication of these initial findings is necessary. These data will serve as a resource for replication as more genes become identified with BMI and WC.

-  MalaCards Disease Associations
  MalaCards Gene Search: TEX15
Diseases sorted by gene-association score: azoospermia (5)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 8.08 RPKM in Testis
Total median expression: 15.53 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -13.5068-0.199 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologGenome BrowserNo orthologGenome BrowserNo ortholog
Gene Details   Gene Details 
Gene Sorter   Gene Sorter 
  Ensembl WormBase 
  Protein Sequence Protein Sequence 
  Alignment Alignment 

-  Descriptions from all associated GenBank mRNAs
  BC140934 - Homo sapiens testis expressed 15, mRNA (cDNA clone MGC:176611 IMAGE:9056746), complete cds.
AF285605 - Homo sapiens testis protein TEX15 (TEX15) mRNA, complete cds.
BC141841 - Homo sapiens testis expressed 15, mRNA (cDNA clone IMAGE:8860305), partial cds.

-  Other Names for This Gene
  Alternate Gene Symbols: BC141841
UCSC ID: uc011lbc.2
Representative RNA: BC141841

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: BC141841.1
exon count: 7CDS single in 3' UTR: no RNA size: 1534
ORF size: 1452CDS single in intron: no Alignment % ID: 99.87
txCdsPredict score: 3031.50frame shift in genome: no % Coverage: 99.02
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: no retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.