Description: Homo sapiens A kinase (PRKA) anchor protein 2 (PALM2AKAP2), transcript variant 3, mRNA. RefSeq Summary (NM_001198656): This gene belongs to the paralemmin downstream gene (PDG) family defined in PMID:22855693. Paralemmin downstream genes may have evolved contiguously with the paralemmin genes and are associated with other paralemmin paralogs in humans and several other taxa. The gene encodes three distinct protein isoforms, the PALM2 isoform, the AKAP2 isoform and the PALM2-AKAP2 isoform. The biological significance of the PALM2-AKAP2 isoforms is yet unknown. Earlier, PALM2 and AKAP2 were annotated as separate genes and PALM2-AKAP2 was annotated as a readthrough gene. [provided by RefSeq, May 2019]. Transcript (Including UTRs) Position: hg19 chr9:112,810,878-112,934,791 Size: 123,914 Total Exon Count: 5 Strand: + Coding Region Position: hg19 chr9:112,810,980-112,930,777 Size: 119,798 Coding Exon Count: 5
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
Pfam Domains: PF15304 - A-kinase anchor protein 2 C-terminus
ModBase Predicted Comparative 3D Structure on Q9Y2D5-7
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
