Human Gene RALGPS1 (uc011mab.2)
Description: Homo sapiens Ral GEF with PH domain and SH3 binding motif 1 (RALGPS1), transcript variant 4, mRNA.
Transcript (Including UTRs)
Position: hg19 chr9:129,677,053-129,946,603 Size: 269,551 Total Exon Count: 12 Strand: +
Coding Region
Position: hg19 chr9:129,724,569-129,946,390 Size: 221,822 Coding Exon Count: 11
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Primer design for this transcript
Genetic Association Studies of Complex Diseases and Disorders
Genetic Association Database (archive): RALGPS1
CDC HuGE Published Literature: RALGPS1
Positive Disease Associations: Body Mass Index
Related Studies: Body Mass Index , , .
[PubMed 0 ]
Comparative Toxicogenomics Database (CTD)
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
Pfam Domains: PF00617 - RasGEF domain
SCOP Domains: 48366 - Ras GEF
ModBase Predicted Comparative 3D Structure on Q5JS13-3
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse Rat Zebrafish D. melanogaster C. elegans S. cerevisiae
No ortholog No ortholog No ortholog No ortholog No ortholog No ortholog
Gene Details
Gene Sorter
Descriptions from all associated GenBank mRNAs
AB002349 - Homo sapiens mRNA for KIAA0351 gene.BC033708 - Homo sapiens Ral GEF with PH domain and SH3 binding motif 1, mRNA (cDNA clone MGC:45125 IMAGE:3901593), complete cds.AK299149 - Homo sapiens cDNA FLJ61342 complete cds, highly similar to Homo sapiens Ral GEF with PH domain and SH3 binding motif 1 (RALGPS1), mRNA.BC032372 - Homo sapiens Ral GEF with PH domain and SH3 binding motif 1, mRNA (cDNA clone MGC:40302 IMAGE:5163332), complete cds.AF221098 - Homo sapiens Ral guanine nucleotide exchange factor RalGPS1A mRNA, complete cds.CU689706 - Synthetic construct Homo sapiens gateway clone IMAGE:100018190 5' read RALGPS1 mRNA.AB385313 - Synthetic construct DNA, clone: pF1KA0351, Homo sapiens RALGPS1 gene for ral GEF with PH domain and SH3 binding motif 1, complete cds, without stop codon, in Flexi system.BX648170 - Homo sapiens mRNA; cDNA DKFZp686K169 (from clone DKFZp686K169).JD158026 - Sequence 139050 from Patent EP1572962.BC019329 - Homo sapiens Ral GEF with PH domain and SH3 binding motif 1, mRNA (cDNA clone IMAGE:3503102), partial cds.JD216856 - Sequence 197880 from Patent EP1572962.JD382190 - Sequence 363214 from Patent EP1572962.JD338062 - Sequence 319086 from Patent EP1572962.JD167569 - Sequence 148593 from Patent EP1572962.
Other Names for This Gene
Alternate Gene Symbols: BC033708, KIAA0351, NM_001190730, NP_001177659, Q5JS13-3, RALGEF2UCSC ID: uc011mab.2RefSeq Accession: NM_001190730
Protein: Q5JS13-3 , splice isoform of Q5JS13
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
BC033708.1
exon count:
12 CDS single in 3' UTR:
no
RNA size:
1678
ORF size:
1155 CDS single in intron:
no
Alignment % ID:
99.76
txCdsPredict score:
2211.00 frame shift in genome:
no
% Coverage:
98.57
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
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Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.