Human Gene TMEM92 (uc021tzz.1)
Description: Homo sapiens transmembrane protein 92 (TMEM92), transcript variant 1, mRNA.
Transcript (Including UTRs)
Position: hg19 chr17:48,351,788-48,358,846 Size: 7,059 Total Exon Count: 5 Strand: +
Coding Region
Position: hg19 chr17:48,351,863-48,356,669 Size: 4,807 Coding Exon Count: 5
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: TMM92_HUMAN
DESCRIPTION: RecName: Full=Transmembrane protein 92; Flags: Precursor;
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein (Potential).
Primer design for this transcript
Genetic Association Studies of Complex Diseases and Disorders
Genetic Association Database (archive): TMEM92
CDC HuGE Published Literature: TMEM92
Positive Disease Associations: Lipoproteins
Related Studies: Lipoproteins , , .
[PubMed 0 ]
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
Pfam Domains: PF11669 - WW domain-binding protein 1
ModBase Predicted Comparative 3D Structure on Q6UXU6
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse Rat Zebrafish D. melanogaster C. elegans S. cerevisiae
No ortholog No ortholog No ortholog No ortholog No ortholog No ortholog
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
AY358204 - Homo sapiens clone DNA131647 SQAW5801 (UNQ5801) mRNA, complete cds.AK090637 - Homo sapiens cDNA FLJ33318 fis, clone BNGH42007594.AX746552 - Sequence 77 from Patent EP1308459.JD123065 - Sequence 104089 from Patent EP1572962.BC064507 - Homo sapiens transmembrane protein 92, mRNA (cDNA clone MGC:71131 IMAGE:6455254), complete cds.KJ900347 - Synthetic construct Homo sapiens clone ccsbBroadEn_09741 TMEM92 gene, encodes complete protein.JD095149 - Sequence 76173 from Patent EP1572962.JD545685 - Sequence 526709 from Patent EP1572962.JD099566 - Sequence 80590 from Patent EP1572962.JD067167 - Sequence 48191 from Patent EP1572962.JD235507 - Sequence 216531 from Patent EP1572962.JD365601 - Sequence 346625 from Patent EP1572962.JD227168 - Sequence 208192 from Patent EP1572962.JD421828 - Sequence 402852 from Patent EP1572962.JD541199 - Sequence 522223 from Patent EP1572962.JD458816 - Sequence 439840 from Patent EP1572962.JD455178 - Sequence 436202 from Patent EP1572962.JD507274 - Sequence 488298 from Patent EP1572962.JD052624 - Sequence 33648 from Patent EP1572962.JD367405 - Sequence 348429 from Patent EP1572962.JD152680 - Sequence 133704 from Patent EP1572962.JD480789 - Sequence 461813 from Patent EP1572962.JD283964 - Sequence 264988 from Patent EP1572962.JD231521 - Sequence 212545 from Patent EP1572962.JD335451 - Sequence 316475 from Patent EP1572962.JD118664 - Sequence 99688 from Patent EP1572962.JD099893 - Sequence 80917 from Patent EP1572962.JD183039 - Sequence 164063 from Patent EP1572962.JD050697 - Sequence 31721 from Patent EP1572962.JD480704 - Sequence 461728 from Patent EP1572962.JD104390 - Sequence 85414 from Patent EP1572962.JD424355 - Sequence 405379 from Patent EP1572962.JD202715 - Sequence 183739 from Patent EP1572962.JD363439 - Sequence 344463 from Patent EP1572962.JD544438 - Sequence 525462 from Patent EP1572962.JD038495 - Sequence 19519 from Patent EP1572962.JD454673 - Sequence 435697 from Patent EP1572962.JD352798 - Sequence 333822 from Patent EP1572962.JD497089 - Sequence 478113 from Patent EP1572962.JD475332 - Sequence 456356 from Patent EP1572962.JD130845 - Sequence 111869 from Patent EP1572962.JD324324 - Sequence 305348 from Patent EP1572962.JD414020 - Sequence 395044 from Patent EP1572962.JD180994 - Sequence 162018 from Patent EP1572962.JD349339 - Sequence 330363 from Patent EP1572962.JD347899 - Sequence 328923 from Patent EP1572962.JD081262 - Sequence 62286 from Patent EP1572962.JD170888 - Sequence 151912 from Patent EP1572962.JD146269 - Sequence 127293 from Patent EP1572962.JD304149 - Sequence 285173 from Patent EP1572962.JD130940 - Sequence 111964 from Patent EP1572962.
Other Names for This Gene
Alternate Gene Symbols: NM_153229, NP_694961, Q6UXU6, Q8NBF0, TMM92_HUMAN, UNQ5801/PRO19608UCSC ID: uc021tzz.1RefSeq Accession: NM_153229
Protein: Q6UXU6
(aka TMM92_HUMAN)
CCDS: CCDS11562.1
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
NM_153229.2
exon count:
5 CDS single in 3' UTR:
no
RNA size:
2747
ORF size:
480 CDS single in intron:
no
Alignment % ID:
100.00
txCdsPredict score:
1160.00 frame shift in genome:
no
% Coverage:
99.45
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
49 # strange splices:
0
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Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.