Human Gene NIBAN3 (uc021uqi.1)
  Description: Homo sapiens family with sequence similarity 129, member C (NIBAN3), transcript variant 2, mRNA.
Transcript (Including UTRs)
   Position: hg19 chr19:17,634,110-17,662,835 Size: 28,726 Total Exon Count: 16 Strand: +
Coding Region
   Position: hg19 chr19:17,634,248-17,662,707 Size: 28,460 Coding Exon Count: 16 

Page IndexSequence and LinksPrimersGene AllelesRNA-Seq ExpressionMicroarray Expression
RNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Methods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr19:17,634,110-17,662,835)mRNA (may differ from genome)Protein (651 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaAlphaFoldBioGPS
EnsemblEntrez GeneExonPrimerGeneCardsGeneNetworkH-INV
LynxMGIOMIMPubMedTreefamUniProtKB
BioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 22.37 RPKM in Spleen
Total median expression: 36.18 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -47.00138-0.341 Picture PostScript Text
3' UTR -21.30128-0.166 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  SCOP Domains:
50729 - PH domain-like

ModBase Predicted Comparative 3D Structure on Q86XR2-3
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGD    
 Protein Sequence    
 Alignment    

-  Descriptions from all associated GenBank mRNAs
  AY254197 - Homo sapiens B-cell novel protein isoform 1 mRNA, complete cds.
AY254198 - Homo sapiens B-cell novel protein isoform 2 mRNA, complete cds.
AY254199 - Homo sapiens B-cell novel protein isoform 3 mRNA, complete cds.
JD333459 - Sequence 314483 from Patent EP1572962.
JD180897 - Sequence 161921 from Patent EP1572962.
BC167806 - Synthetic construct Homo sapiens clone IMAGE:100068196, MGC:195813 family with sequence similarity 129, member C (FAM129C) mRNA, encodes complete protein.
AK300046 - Homo sapiens cDNA FLJ57001 complete cds, highly similar to Homo sapiens B-cell novel protein 1 (BCNP1), mRNA.
AK097121 - Homo sapiens cDNA FLJ39802 fis, clone SPLEN2007750, weakly similar to Mus musculus Niban mRNA.
AK298062 - Homo sapiens cDNA FLJ52339 complete cds, highly similar to Homo sapiens B-cell novel protein 1 (BCNP1), mRNA.
AK074069 - Homo sapiens mRNA for FLJ00140 protein.
AK301159 - Homo sapiens cDNA FLJ55143 complete cds, highly similar to Homo sapiens B-cell novel protein 1 (BCNP1), mRNA.
BC053606 - Homo sapiens family with sequence similarity 129, member C, mRNA (cDNA clone IMAGE:6012210), partial cds.
BC033225 - Homo sapiens family with sequence similarity 129, member C, mRNA (cDNA clone IMAGE:5088150), with apparent retained intron.
JD157127 - Sequence 138151 from Patent EP1572962.
JD149606 - Sequence 130630 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: BCNP1, FAM129C, NM_001098524, NP_001091994, Q86XR2-3
UCSC ID: uc021uqi.1
RefSeq Accession: NM_001098524
Protein: Q86XR2-3 CCDS: CCDS42521.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_001098524.1
exon count: 16CDS single in 3' UTR: no RNA size: 2233
ORF size: 1956CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 3818.00frame shift in genome: no % Coverage: 99.37
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.