Human Gene FAM76A (ENST00000373954.11) from GENCODE V44
  Description: Homo sapiens family with sequence similarity 76 member A (FAM76A), transcript variant 3, mRNA. (from RefSeq NM_152660)
Gencode Transcript: ENST00000373954.11
Gencode Gene: ENSG00000009780.16
Transcript (Including UTRs)
   Position: hg38 chr1:27,725,961-27,763,116 Size: 37,156 Total Exon Count: 9 Strand: +
Coding Region
   Position: hg38 chr1:27,726,081-27,760,581 Size: 34,501 Coding Exon Count: 9 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA Descriptions
Other NamesMethods
Data last updated at UCSC: 2023-08-18 00:09:47

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr1:27,725,961-27,763,116)mRNA (may differ from genome)Protein (307 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaAlphaFoldBioGPS
EnsemblEntrez GeneExonPrimerGencodeGeneCardsHGNC
LynxMalacardsMGIneXtProtPubMedUniProtKB
WikipediaBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: FA76A_HUMAN
DESCRIPTION: RecName: Full=Protein FAM76A;
SIMILARITY: Belongs to the FAM76 family.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 9.26 RPKM in Testis
Total median expression: 198.53 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -58.00120-0.483 Picture PostScript Text
3' UTR -660.102535-0.260 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on Q8TAV0
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologGenome BrowserGenome BrowserNo ortholog
Gene Details     
Gene Sorter     
MGIRGD EnsemblWormBase 
Protein SequenceProtein Sequence Protein SequenceProtein Sequence 
AlignmentAlignment AlignmentAlignment 

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Cellular Component:
GO:0005654 nucleoplasm


-  Descriptions from all associated GenBank mRNAs
  BC025768 - Homo sapiens family with sequence similarity 76, member A, mRNA (cDNA clone MGC:34648 IMAGE:5211010), complete cds.
LF383917 - JP 2014500723-A/191420: Polycomb-Associated Non-Coding RNAs.
MA619494 - JP 2018138019-A/191420: Polycomb-Associated Non-Coding RNAs.
AK290120 - Homo sapiens cDNA FLJ78322 complete cds.
JD156179 - Sequence 137203 from Patent EP1572962.
AK301672 - Homo sapiens cDNA FLJ52921 complete cds, moderately similar to Protein FAM76A.
JD458561 - Sequence 439585 from Patent EP1572962.
JD414099 - Sequence 395123 from Patent EP1572962.
AK310165 - Homo sapiens cDNA, FLJ17207.
AK098318 - Homo sapiens cDNA FLJ40999 fis, clone UTERU2016426.
AL035307 - H.sapiens gene from PAC 426I6.
AL035309 - H.sapiens gene from PAC 426I6.
CU693060 - Synthetic construct Homo sapiens gateway clone IMAGE:100020661 5' read FAM76A mRNA.
HQ447975 - Synthetic construct Homo sapiens clone IMAGE:100071341; CCSB008344_01 family with sequence similarity 76, member A (FAM76A) gene, encodes complete protein.
KJ895788 - Synthetic construct Homo sapiens clone ccsbBroadEn_05182 FAM76A gene, encodes complete protein.
LF356943 - JP 2014500723-A/164446: Polycomb-Associated Non-Coding RNAs.
MA592520 - JP 2018138019-A/164446: Polycomb-Associated Non-Coding RNAs.
LF356936 - JP 2014500723-A/164439: Polycomb-Associated Non-Coding RNAs.
MA592513 - JP 2018138019-A/164439: Polycomb-Associated Non-Coding RNAs.
JD149895 - Sequence 130919 from Patent EP1572962.
JD377858 - Sequence 358882 from Patent EP1572962.
JD535074 - Sequence 516098 from Patent EP1572962.
JD273287 - Sequence 254311 from Patent EP1572962.
JD467483 - Sequence 448507 from Patent EP1572962.
JD509242 - Sequence 490266 from Patent EP1572962.
JD290322 - Sequence 271346 from Patent EP1572962.
JD259344 - Sequence 240368 from Patent EP1572962.
JD487976 - Sequence 469000 from Patent EP1572962.
JD037439 - Sequence 18463 from Patent EP1572962.
LF356935 - JP 2014500723-A/164438: Polycomb-Associated Non-Coding RNAs.
MA592512 - JP 2018138019-A/164438: Polycomb-Associated Non-Coding RNAs.
JD511257 - Sequence 492281 from Patent EP1572962.
JD410835 - Sequence 391859 from Patent EP1572962.
LF356934 - JP 2014500723-A/164437: Polycomb-Associated Non-Coding RNAs.
MA592511 - JP 2018138019-A/164437: Polycomb-Associated Non-Coding RNAs.
JD225075 - Sequence 206099 from Patent EP1572962.
LF356933 - JP 2014500723-A/164436: Polycomb-Associated Non-Coding RNAs.
MA592510 - JP 2018138019-A/164436: Polycomb-Associated Non-Coding RNAs.
JD197989 - Sequence 179013 from Patent EP1572962.
JD135721 - Sequence 116745 from Patent EP1572962.
JD135722 - Sequence 116746 from Patent EP1572962.
JD238310 - Sequence 219334 from Patent EP1572962.
JD238311 - Sequence 219335 from Patent EP1572962.
JD457006 - Sequence 438030 from Patent EP1572962.
AK123940 - Homo sapiens cDNA FLJ41946 fis, clone PLACE6019701.
LF356932 - JP 2014500723-A/164435: Polycomb-Associated Non-Coding RNAs.
MA592509 - JP 2018138019-A/164435: Polycomb-Associated Non-Coding RNAs.
LF356931 - JP 2014500723-A/164434: Polycomb-Associated Non-Coding RNAs.
MA592508 - JP 2018138019-A/164434: Polycomb-Associated Non-Coding RNAs.
LF356930 - JP 2014500723-A/164433: Polycomb-Associated Non-Coding RNAs.
MA592507 - JP 2018138019-A/164433: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: B4DWT3, ENST00000373954.1, ENST00000373954.10, ENST00000373954.2, ENST00000373954.3, ENST00000373954.4, ENST00000373954.5, ENST00000373954.6, ENST00000373954.7, ENST00000373954.8, ENST00000373954.9, FA76A_HUMAN, NM_152660, O95565, O95566, Q8N7J5, Q8TAV0, uc001boq.1, uc001boq.2, uc001boq.3, uc001boq.4, uc001boq.5
UCSC ID: ENST00000373954.11
RefSeq Accession: NM_152660
Protein: Q8TAV0 (aka FA76A_HUMAN)
CCDS: CCDS309.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.