Human Gene LY9 (ENST00000392203.8) from GENCODE V44
Description: Homo sapiens lymphocyte antigen 9 (LY9), transcript variant 4, mRNA. (from RefSeq NM_001261457)
RefSeq Summary (NM_001261457): LY9 belongs to the SLAM family of immunomodulatory receptors (see SLAMF1; MIM 603492) and interacts with the adaptor molecule SAP (SH2D1A; MIM 300490) (Graham et al., 2006 [PubMed 16365421]).[supplied by OMIM, Mar 2008].
Gencode Transcript: ENST00000392203.8
Gencode Gene: ENSG00000122224.18
Transcript (Including UTRs)
Position: hg38 chr1:160,796,112-160,828,255 Size: 32,144 Total Exon Count: 9 Strand: +
Coding Region
Position: hg38 chr1:160,796,188-160,827,816 Size: 31,629 Coding Exon Count: 9
Data last updated at UCSC: 2023-08-18 00:09:47
Sequence and Links to Tools and Databases
Primer design for this transcript
MalaCards Disease Associations
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR007110 - Ig-like
IPR013783 - Ig-like_fold
IPR003599 - Ig_sub
IPR015631 - SLAM_fam_rcpts
ModBase Predicted Comparative 3D Structure on Q5VYH9
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
BC121049 - Homo sapiens lymphocyte antigen 9, mRNA (cDNA clone MGC:149745 IMAGE:40117946), complete cds.AF244129 - Homo sapiens cell-surface molecule Ly-9 mRNA, complete cds.AK292048 - Homo sapiens cDNA FLJ75340 complete cds, highly similar to Homo sapiens cell-surface molecule Ly-9 mRNA.BC027920 - Homo sapiens lymphocyte antigen 9, mRNA (cDNA clone MGC:34782 IMAGE:5225850), complete cds.L42621 - Homo sapiens Ly-9 mRNA, complete cds.AY007142 - Homo sapiens clone CDABP0070 mRNA sequence.KJ901560 - Synthetic construct Homo sapiens clone ccsbBroadEn_10954 LY9 gene, encodes complete protein.BC062589 - Homo sapiens lymphocyte antigen 9, mRNA (cDNA clone IMAGE:5215651).AF055708 - Homo sapiens lymphocyte antigen 9 precursor (LY9) mRNA, alternatively spliced, partial cds.AF055709 - Homo sapiens lymphocyte antigen 9 precursor (LY9) mRNA, partial cds.AK303403 - Homo sapiens cDNA FLJ56843 complete cds, highly similar to T-lymphocyte surface antigen Ly-9 precursor.HQ447693 - Synthetic construct Homo sapiens clone IMAGE:100071021; CCSB013751_01 lymphocyte antigen 9 (LY9) gene, encodes complete protein.KJ891559 - Synthetic construct Homo sapiens clone ccsbBroadEn_00953 LY9 gene, encodes complete protein.BC042905 - Homo sapiens lymphocyte antigen 9, mRNA (cDNA clone IMAGE:5932767).BC064485 - Homo sapiens lymphocyte antigen 9, mRNA (cDNA clone IMAGE:5483404), complete cds.AK128573 - Homo sapiens cDNA FLJ46732 fis, clone TRACH3019807.JD202587 - Sequence 183611 from Patent EP1572962.JD302182 - Sequence 283206 from Patent EP1572962.JD071629 - Sequence 52653 from Patent EP1572962.JD544679 - Sequence 525703 from Patent EP1572962.JD099417 - Sequence 80441 from Patent EP1572962.JD207453 - Sequence 188477 from Patent EP1572962.JD497309 - Sequence 478333 from Patent EP1572962.JD289858 - Sequence 270882 from Patent EP1572962.JD432145 - Sequence 413169 from Patent EP1572962.JD508559 - Sequence 489583 from Patent EP1572962.JD166340 - Sequence 147364 from Patent EP1572962.JD039792 - Sequence 20816 from Patent EP1572962.
Other Names for This Gene
Alternate Gene Symbols: ENST00000392203.1, ENST00000392203.2, ENST00000392203.3, ENST00000392203.4, ENST00000392203.5, ENST00000392203.6, ENST00000392203.7, NM_001261457, Q5VYH9, Q5VYH9_HUMAN, RP11-312J18.1-002, uc001fww.1, uc001fww.2, uc001fww.3, uc001fww.4, uc001fww.5UCSC ID: ENST00000392203.8RefSeq Accession: NM_001261457
Protein: Q5VYH9
CCDS: CCDS65696.1
Methods, Credits, and Use Restrictions
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