The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on O75152
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding GO:0003723 RNA binding GO:0005515 protein binding GO:0046872 metal ion binding
Biological Process: GO:0006357 regulation of transcription from RNA polymerase II promoter GO:0006405 RNA export from nucleus GO:0006406 mRNA export from nucleus GO:0016973 poly(A)+ mRNA export from nucleus GO:0031124 mRNA 3'-end processing GO:0051028 mRNA transport
CR627439 - Homo sapiens mRNA; cDNA DKFZp781G2455 (from clone DKFZp781G2455). AK095858 - Homo sapiens cDNA FLJ38539 fis, clone HCHON2001450. AK296983 - Homo sapiens cDNA FLJ58196 complete cds, highly similar to Zinc finger CCCH domain-containing protein 11A. BC014268 - Homo sapiens zinc finger CCCH-type containing 11A, mRNA (cDNA clone MGC:10420 IMAGE:3844154), complete cds. BC038513 - Homo sapiens zinc finger CCCH-type containing 11A, mRNA (cDNA clone IMAGE:5262797). BX649148 - Homo sapiens mRNA; cDNA DKFZp686F14109 (from clone DKFZp686F14109). CR627446 - Homo sapiens mRNA; cDNA DKFZp686D03108 (from clone DKFZp686D03108). BX648271 - Homo sapiens mRNA; cDNA DKFZp686C10119 (from clone DKFZp686C10119). BC048271 - Homo sapiens zinc finger CCCH-type containing 11A, mRNA (cDNA clone IMAGE:4452836), containing frame-shift errors. AB014563 - Homo sapiens KIAA0663 mRNA for KIAA0663 protein. JD465569 - Sequence 446593 from Patent EP1572962. JD067215 - Sequence 48239 from Patent EP1572962. LP895733 - Sequence 597 from Patent EP3253886. JD466300 - Sequence 447324 from Patent EP1572962. BC046137 - Homo sapiens zinc finger CCCH-type containing 11A, mRNA (cDNA clone IMAGE:4413044), complete cds. JD560174 - Sequence 541198 from Patent EP1572962. JD296771 - Sequence 277795 from Patent EP1572962. JD290652 - Sequence 271676 from Patent EP1572962. CU676953 - Synthetic construct Homo sapiens gateway clone IMAGE:100020417 5' read ZC3H11A mRNA. KJ892869 - Synthetic construct Homo sapiens clone ccsbBroadEn_02263 ZC3H11A gene, encodes complete protein. AB383947 - Synthetic construct DNA, clone: pF1KSDA0663, Homo sapiens ZC3H11A gene for zinc finger CCCH-type containing protein 11A, complete cds, without stop codon, in Flexi system. AK310470 - Homo sapiens cDNA, FLJ17512.
Biochemical and Signaling Pathways
Reactome (by CSHL, EBI, and GO)
Protein O75152 (Reactome details) participates in the following event(s):
R-HSA-8849157 TREX complex binds spliced, capped mRNA:CBC:EJC cotranscriptionally R-HSA-75096 Docking of the TAP:EJC Complex with the NPC R-HSA-72185 mRNA polyadenylation R-HSA-72180 Cleavage of mRNA at the 3'-end R-HSA-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) R-HSA-72187 mRNA 3'-end processing R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA R-HSA-72202 Transport of Mature Transcript to Cytoplasm R-HSA-109688 Cleavage of Growing Transcript in the Termination Region R-HSA-8953854 Metabolism of RNA R-HSA-73856 RNA Polymerase II Transcription Termination R-HSA-73857 RNA Polymerase II Transcription R-HSA-74160 Gene expression (Transcription)
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