Human Gene C1orf198 (ENST00000427697.2) from GENCODE V44
  Description: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. (from UniProt E5RFY9)
Gencode Transcript: ENST00000427697.2
Gencode Gene: ENSG00000119280.17
Transcript (Including UTRs)
   Position: hg38 chr1:230,837,120-230,869,316 Size: 32,197 Total Exon Count: 4 Strand: -
Coding Region
   Position: hg38 chr1:230,839,852-230,843,629 Size: 3,778 Coding Exon Count: 2 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther Names
Methods
Data last updated at UCSC: 2023-08-18 00:09:47

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr1:230,837,120-230,869,316)mRNA (may differ from genome)Protein (110 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaAlphaFold
BioGPSEnsemblExonPrimerGencodeGeneCardsHGNC
LynxMGIPubMedUniProtKBWikipedia

-  Comments and Description Text from UniProtKB
  ID: E5RFY9_HUMAN
DESCRIPTION: SubName: Full=Uncharacterized protein C1orf198;
CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 64.97 RPKM in Brain - Spinal cord (cervical c-1)
Total median expression: 1103.22 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -255.30601-0.425 Picture PostScript Text
3' UTR -841.002732-0.308 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on E5RFY9
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
MGIRGD    
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Descriptions from all associated GenBank mRNAs
  AL833809 - Homo sapiens mRNA; cDNA DKFZp564C083 (from clone DKFZp564C083).
BC004870 - Homo sapiens chromosome 1 open reading frame 198, mRNA (cDNA clone IMAGE:3844339).
AL713769 - Homo sapiens mRNA; cDNA DKFZp667D152 (from clone DKFZp667D152).
BC066649 - Homo sapiens chromosome 1 open reading frame 198, mRNA (cDNA clone MGC:74828 IMAGE:6011914), complete cds.
AK027431 - Homo sapiens cDNA FLJ14525 fis, clone NT2RM1001105.
AK131306 - Homo sapiens cDNA FLJ16283 fis, clone NT2RI3005928.
JD443633 - Sequence 424657 from Patent EP1572962.
JD127177 - Sequence 108201 from Patent EP1572962.
JD328659 - Sequence 309683 from Patent EP1572962.
JD357635 - Sequence 338659 from Patent EP1572962.
JD183495 - Sequence 164519 from Patent EP1572962.
JD385091 - Sequence 366115 from Patent EP1572962.
JD327817 - Sequence 308841 from Patent EP1572962.
JD097944 - Sequence 78968 from Patent EP1572962.
JD338262 - Sequence 319286 from Patent EP1572962.
JD182911 - Sequence 163935 from Patent EP1572962.
JD056337 - Sequence 37361 from Patent EP1572962.
JD478984 - Sequence 460008 from Patent EP1572962.
JD528334 - Sequence 509358 from Patent EP1572962.
JD456891 - Sequence 437915 from Patent EP1572962.
JD225494 - Sequence 206518 from Patent EP1572962.
JD229036 - Sequence 210060 from Patent EP1572962.
JD316600 - Sequence 297624 from Patent EP1572962.
JD097970 - Sequence 78994 from Patent EP1572962.
JD223471 - Sequence 204495 from Patent EP1572962.
JD243764 - Sequence 224788 from Patent EP1572962.
JD545517 - Sequence 526541 from Patent EP1572962.
JD399723 - Sequence 380747 from Patent EP1572962.
JD304917 - Sequence 285941 from Patent EP1572962.
JD286411 - Sequence 267435 from Patent EP1572962.
JD244978 - Sequence 226002 from Patent EP1572962.
JD195578 - Sequence 176602 from Patent EP1572962.
JD126291 - Sequence 107315 from Patent EP1572962.
JD327850 - Sequence 308874 from Patent EP1572962.
JD240012 - Sequence 221036 from Patent EP1572962.
AK096166 - Homo sapiens cDNA FLJ38847 fis, clone MESAN2007597.
JD305353 - Sequence 286377 from Patent EP1572962.
JD310430 - Sequence 291454 from Patent EP1572962.
JD427177 - Sequence 408201 from Patent EP1572962.
JD540707 - Sequence 521731 from Patent EP1572962.
JD273936 - Sequence 254960 from Patent EP1572962.
JD336217 - Sequence 317241 from Patent EP1572962.
JD429622 - Sequence 410646 from Patent EP1572962.
JD142031 - Sequence 123055 from Patent EP1572962.
JD329744 - Sequence 310768 from Patent EP1572962.
JD190329 - Sequence 171353 from Patent EP1572962.
JD282038 - Sequence 263062 from Patent EP1572962.
JD250268 - Sequence 231292 from Patent EP1572962.
JD052316 - Sequence 33340 from Patent EP1572962.
JD106383 - Sequence 87407 from Patent EP1572962.
JD124547 - Sequence 105571 from Patent EP1572962.
JD052279 - Sequence 33303 from Patent EP1572962.
JD456060 - Sequence 437084 from Patent EP1572962.
JD038962 - Sequence 19986 from Patent EP1572962.
JD120828 - Sequence 101852 from Patent EP1572962.
AK292433 - Homo sapiens cDNA FLJ75046 complete cds.
JD539012 - Sequence 520036 from Patent EP1572962.
JD279391 - Sequence 260415 from Patent EP1572962.
JD312398 - Sequence 293422 from Patent EP1572962.
JD299919 - Sequence 280943 from Patent EP1572962.
KJ895047 - Synthetic construct Homo sapiens clone ccsbBroadEn_04441 C1orf198 gene, encodes complete protein.

-  Other Names for This Gene
  Alternate Gene Symbols: AK131306, E5RFY9, E5RFY9_HUMAN, ENST00000427697.1, uc001huc.1, uc001huc.2, uc001huc.3
UCSC ID: ENST00000427697.2
RefSeq Accession: NM_001136494
Protein: E5RFY9

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.