Human Gene LTO1 (ENST00000536870.5) from GENCODE V44
  Description: LTO1 (from geneSymbol)
Gencode Transcript: ENST00000536870.5
Gencode Gene: ENSG00000149716.13
Transcript (Including UTRs)
   Position: hg38 chr11:69,665,566-69,675,323 Size: 9,758 Total Exon Count: 3 Strand: -
Coding Region
   Position: hg38 chr11:69,667,519-69,675,239 Size: 7,721 Coding Exon Count: 3 

Page IndexSequence and LinksPrimersRNA-Seq ExpressionMicroarray ExpressionRNA Structure
Protein StructureOther SpeciesmRNA DescriptionsOther NamesMethods
Data last updated at UCSC: 2023-08-18 00:09:47

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr11:69,665,566-69,675,323)mRNA (may differ from genome)Protein (78 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaAlphaFoldBioGPS
EnsemblExonPrimerGencodeGeneCardsMalacardsMGI
PubMedUniProtKB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 6.35 RPKM in Spleen
Total median expression: 204.30 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -38.6084-0.460 Picture PostScript Text
3' UTR -720.601953-0.369 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on F5GWS9
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
MGIRGD    
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Descriptions from all associated GenBank mRNAs
  AK294004 - Homo sapiens cDNA FLJ58145 complete cds, highly similar to Oral cancer overexpressed protein 1.
BC006448 - Homo sapiens oral cancer overexpressed 1, mRNA (cDNA clone IMAGE:3637085).
BC019024 - Homo sapiens oral cancer overexpressed 1, mRNA (cDNA clone MGC:20857 IMAGE:4544931), complete cds.
BC065542 - Homo sapiens oral cancer overexpressed 1, mRNA (cDNA clone MGC:70446 IMAGE:6101144), complete cds.
AF503940 - Homo sapiens TAOS1 (ORAOV1) mRNA, complete cds.
AK126490 - Homo sapiens cDNA FLJ44526 fis, clone UTERU3003465.
AK125280 - Homo sapiens cDNA FLJ43290 fis, clone MESAN2014295.
JD550928 - Sequence 531952 from Patent EP1572962.
JD111058 - Sequence 92082 from Patent EP1572962.
JD508544 - Sequence 489568 from Patent EP1572962.
JD451951 - Sequence 432975 from Patent EP1572962.
JD435561 - Sequence 416585 from Patent EP1572962.
JD429577 - Sequence 410601 from Patent EP1572962.
JD477395 - Sequence 458419 from Patent EP1572962.
JD535757 - Sequence 516781 from Patent EP1572962.
JD272724 - Sequence 253748 from Patent EP1572962.
JD081577 - Sequence 62601 from Patent EP1572962.
JD157620 - Sequence 138644 from Patent EP1572962.
JD311782 - Sequence 292806 from Patent EP1572962.
JD094115 - Sequence 75139 from Patent EP1572962.
JD064670 - Sequence 45694 from Patent EP1572962.
JD242927 - Sequence 223951 from Patent EP1572962.
JD153332 - Sequence 134356 from Patent EP1572962.
JD215812 - Sequence 196836 from Patent EP1572962.
JD272553 - Sequence 253577 from Patent EP1572962.
JD453854 - Sequence 434878 from Patent EP1572962.
JD466205 - Sequence 447229 from Patent EP1572962.
JD525091 - Sequence 506115 from Patent EP1572962.
JD098135 - Sequence 79159 from Patent EP1572962.
JD347217 - Sequence 328241 from Patent EP1572962.
JD113581 - Sequence 94605 from Patent EP1572962.
JD398857 - Sequence 379881 from Patent EP1572962.
AK054816 - Homo sapiens cDNA FLJ30254 fis, clone BRACE2002441, highly similar to Ferritin heavy chain (EC 1.16.3.1).
JD416580 - Sequence 397604 from Patent EP1572962.
JD069274 - Sequence 50298 from Patent EP1572962.
JD118639 - Sequence 99663 from Patent EP1572962.
JD088356 - Sequence 69380 from Patent EP1572962.
JD553744 - Sequence 534768 from Patent EP1572962.
JD396702 - Sequence 377726 from Patent EP1572962.
JD231274 - Sequence 212298 from Patent EP1572962.
JD520513 - Sequence 501537 from Patent EP1572962.
EF639695 - Homo sapiens oral cancer overexpressed protein 1-A (ORAOV1) mRNA, complete cds, alternatively spliced.
JX460858 - Homo sapiens oral cancer overexpressed 1 (ORAOV1) mRNA, partial cds, alternatively spliced.
KC427269 - Homo sapiens non-coding RNA oral cancer-overexpressed 1 (ORAOV1), partial sequence, alternatively spliced.
AK311918 - Homo sapiens cDNA, FLJ92185, Homo sapiens oral cancer overexpressed 1 (ORAOV1), mRNA.
KJ895846 - Synthetic construct Homo sapiens clone ccsbBroadEn_05240 ORAOV1 gene, encodes complete protein.
AK026600 - Homo sapiens cDNA: FLJ22947 fis, clone KAT09234.
JD102290 - Sequence 83314 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: AK125280, ENST00000536870.1, ENST00000536870.2, ENST00000536870.3, ENST00000536870.4, F5GWS9, F5GWS9_HUMAN, ORAOV1, uc001opd.1, uc001opd.2, uc001opd.3, uc001opd.4
UCSC ID: ENST00000536870.5
RefSeq Accession: NM_153451
Protein: F5GWS9

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.