Human Gene TMEM19 (ENST00000266673.10) from GENCODE V49
Description: transmembrane protein 19 (from RefSeq NM_018279.4)Gencode Transcript: ENST00000266673.10Gencode Gene: ENSG00000139291.15Transcript (Including UTRs) Position: hg38 chr12:71,686,082-71,705,047 Size: 18,966 Total Exon Count: 6 Strand: +Coding Region Position: hg38 chr12:71,686,681-71,700,995 Size: 14,315 Coding Exon Count: 6
Data last updated at UCSC: 2025-09-17 13:57:07
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: TMM19_HUMAN DESCRIPTION: RecName: Full=Transmembrane protein 19;SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Potential).SIMILARITY: Belongs to the TMEM19 family.
Primer design for this transcript
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
D013749
Tetrachlorodibenzodioxin
D000082
Acetaminophen
D016572
Cyclosporine
C111118
2',3,3',4',5-pentachloro-4-hydroxybiphenyl
C038890
2,3,4,7,8-pentachlorodibenzofuran
C014211
2,3,7,8-tetrachlorodibenzofuran
C472791
3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid
C009505
4,4'-diaminodiphenylmethane
D016604
Aflatoxin B1
D001564
Benzo(a)pyrene
more ... click here to view the complete list
RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR002794 - DUF92_TMEM19Pfam Domains: PF01940 - Integral membrane protein DUF92ModBase Predicted Comparative 3D Structure on Q96HH6 The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
BC008596 - Homo sapiens transmembrane protein 19, mRNA (cDNA clone MGC:16985 IMAGE:4154303), complete cds.AK001798 - Homo sapiens cDNA FLJ10936 fis, clone OVARC1000959, weakly similar to HYPOTHETICAL PROTEIN MJ0933.AK223148 - Homo sapiens mRNA for transmembrane protein 19 variant, clone: LNG01783.AK315587 - Homo sapiens cDNA, FLJ96665.KJ899105 - Synthetic construct Homo sapiens clone ccsbBroadEn_08499 TMEM19 gene, encodes complete protein.JD478200 - Sequence 459224 from Patent EP1572962.JD163515 - Sequence 144539 from Patent EP1572962.JD403961 - Sequence 384985 from Patent EP1572962.JD455672 - Sequence 436696 from Patent EP1572962.JD362771 - Sequence 343795 from Patent EP1572962.JD154897 - Sequence 135921 from Patent EP1572962.JD092845 - Sequence 73869 from Patent EP1572962.JD559287 - Sequence 540311 from Patent EP1572962.JD090501 - Sequence 71525 from Patent EP1572962.JD323197 - Sequence 304221 from Patent EP1572962.AK025839 - Homo sapiens cDNA: FLJ22186 fis, clone HRC01010.JD040328 - Sequence 21352 from Patent EP1572962.JD161104 - Sequence 142128 from Patent EP1572962.JD295618 - Sequence 276642 from Patent EP1572962.JD410168 - Sequence 391192 from Patent EP1572962.JD281750 - Sequence 262774 from Patent EP1572962.JD483680 - Sequence 464704 from Patent EP1572962.JD170271 - Sequence 151295 from Patent EP1572962.JD429374 - Sequence 410398 from Patent EP1572962.JD036369 - Sequence 17393 from Patent EP1572962.JD412910 - Sequence 393934 from Patent EP1572962.JD316350 - Sequence 297374 from Patent EP1572962.JD368264 - Sequence 349288 from Patent EP1572962.JD162657 - Sequence 143681 from Patent EP1572962.JD457391 - Sequence 438415 from Patent EP1572962.JD119264 - Sequence 100288 from Patent EP1572962.JD338085 - Sequence 319109 from Patent EP1572962.JD489298 - Sequence 470322 from Patent EP1572962.JD105631 - Sequence 86655 from Patent EP1572962.JD112077 - Sequence 93101 from Patent EP1572962.JD488563 - Sequence 469587 from Patent EP1572962.JD472397 - Sequence 453421 from Patent EP1572962.JD424731 - Sequence 405755 from Patent EP1572962.JD468175 - Sequence 449199 from Patent EP1572962.JD435057 - Sequence 416081 from Patent EP1572962.JD435058 - Sequence 416082 from Patent EP1572962.JD307210 - Sequence 288234 from Patent EP1572962.JD307212 - Sequence 288236 from Patent EP1572962.JD323098 - Sequence 304122 from Patent EP1572962.JD401884 - Sequence 382908 from Patent EP1572962.JD401885 - Sequence 382909 from Patent EP1572962.JD240824 - Sequence 221848 from Patent EP1572962.JD366386 - Sequence 347410 from Patent EP1572962.JD517516 - Sequence 498540 from Patent EP1572962.JD117013 - Sequence 98037 from Patent EP1572962.JD117015 - Sequence 98039 from Patent EP1572962.JD117014 - Sequence 98038 from Patent EP1572962.
Other Names for This Gene
Alternate Gene Symbols: B2RDL2, ENST00000266673.1, ENST00000266673.2, ENST00000266673.3, ENST00000266673.4, ENST00000266673.5, ENST00000266673.6, ENST00000266673.7, ENST00000266673.8, ENST00000266673.9, NM_018279, Q53FY3, Q96HH6, Q9NV41, TMM19_HUMAN, uc001sws.1, uc001sws.2, uc001sws.3, uc001sws.4, uc001sws.5UCSC ID: ENST00000266673.10RefSeq Accession: NM_018279.4 Protein: Q96HH6
(aka TMM19_HUMAN)CCDS: CCDS9002.1
Methods, Credits, and Use Restrictions
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US Server
Sequence and Links to Tools and Databases 
Microarray Expression Data 
