Human Gene SPRING1 (ENST00000261318.5) from GENCODE V44
Description: Homo sapiens SREBF pathway regulator in golgi 1 (SPRING1), transcript variant 1, mRNA. (from RefSeq NM_024738)
Gencode Transcript: ENST00000261318.5
Gencode Gene: ENSG00000111412.6
Transcript (Including UTRs)
Position: hg38 chr12:116,710,171-116,738,069 Size: 27,899 Total Exon Count: 5 Strand: -
Coding Region
Position: hg38 chr12:116,717,810-116,737,900 Size: 20,091 Coding Exon Count: 5
Data last updated at UCSC: 2023-08-18 00:09:47
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: CL049_HUMAN
DESCRIPTION: RecName: Full=UPF0454 protein C12orf49; Flags: Precursor;
SUBCELLULAR LOCATION: Secreted (Potential).SIMILARITY: Belongs to the UPF0454 family.
Primer design for this transcript
RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR019352 - UPF0454
Pfam Domains: PF10218 - Uncharacterized conserved protein (DUF2054)
ModBase Predicted Comparative 3D Structure on Q9H741
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
AK074371 - Homo sapiens cDNA FLJ23791 fis, clone HEP21711.JD060220 - Sequence 41244 from Patent EP1572962.JD413729 - Sequence 394753 from Patent EP1572962.JD463087 - Sequence 444111 from Patent EP1572962.JD337563 - Sequence 318587 from Patent EP1572962.JD533826 - Sequence 514850 from Patent EP1572962.JD371268 - Sequence 352292 from Patent EP1572962.JD514431 - Sequence 495455 from Patent EP1572962.JD414475 - Sequence 395499 from Patent EP1572962.JD524694 - Sequence 505718 from Patent EP1572962.AK025068 - Homo sapiens cDNA: FLJ21415 fis, clone COL04030.JD448042 - Sequence 429066 from Patent EP1572962.JD039140 - Sequence 20164 from Patent EP1572962.JD297172 - Sequence 278196 from Patent EP1572962.JD183558 - Sequence 164582 from Patent EP1572962.JD122988 - Sequence 104012 from Patent EP1572962.JD240110 - Sequence 221134 from Patent EP1572962.JD137335 - Sequence 118359 from Patent EP1572962.JD137334 - Sequence 118358 from Patent EP1572962.JD229271 - Sequence 210295 from Patent EP1572962.JD091767 - Sequence 72791 from Patent EP1572962.JD318090 - Sequence 299114 from Patent EP1572962.JD049058 - Sequence 30082 from Patent EP1572962.JD157454 - Sequence 138478 from Patent EP1572962.JD435964 - Sequence 416988 from Patent EP1572962.JD384382 - Sequence 365406 from Patent EP1572962.JD427522 - Sequence 408546 from Patent EP1572962.JD540340 - Sequence 521364 from Patent EP1572962.AK309652 - Homo sapiens cDNA, FLJ99693.JD288013 - Sequence 269037 from Patent EP1572962.JD358282 - Sequence 339306 from Patent EP1572962.BC019843 - Homo sapiens chromosome 12 open reading frame 49, mRNA (cDNA clone MGC:29833 IMAGE:5112874), complete cds.JD089889 - Sequence 70913 from Patent EP1572962.AK222983 - Homo sapiens mRNA for hypothetical protein FLJ21415 variant, clone: HSI04906.JD207061 - Sequence 188085 from Patent EP1572962.AK298857 - Homo sapiens cDNA FLJ52021 complete cds.JD434790 - Sequence 415814 from Patent EP1572962.JD201710 - Sequence 182734 from Patent EP1572962.JD187761 - Sequence 168785 from Patent EP1572962.JD216388 - Sequence 197412 from Patent EP1572962.JD398959 - Sequence 379983 from Patent EP1572962.JD191263 - Sequence 172287 from Patent EP1572962.JD544924 - Sequence 525948 from Patent EP1572962.JD187435 - Sequence 168459 from Patent EP1572962.JD535582 - Sequence 516606 from Patent EP1572962.JD229563 - Sequence 210587 from Patent EP1572962.JD221805 - Sequence 202829 from Patent EP1572962.JD220189 - Sequence 201213 from Patent EP1572962.KJ894733 - Synthetic construct Homo sapiens clone ccsbBroadEn_04127 C12orf49 gene, encodes complete protein.DQ581320 - Homo sapiens piRNA piR-49432, complete sequence.DQ599635 - Homo sapiens piRNA piR-37701, complete sequence.JD271323 - Sequence 252347 from Patent EP1572962.JD422381 - Sequence 403405 from Patent EP1572962.
Other Names for This Gene
Alternate Gene Symbols: C12orf49, CL049_HUMAN, ENST00000261318.1, ENST00000261318.2, ENST00000261318.3, ENST00000261318.4, NM_024738, Q53GE8, Q9H741, uc001tvz.1, uc001tvz.2, uc001tvz.3UCSC ID: ENST00000261318.5RefSeq Accession: NM_024738
Protein: Q9H741
(aka CL049_HUMAN)
CCDS: CCDS9179.1
Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.