Human Gene BRF1 (ENST00000635152.1) from GENCODE V44
Description: BRF1, RNA polymerase III transcription initiation factor subunit (from HGNC BRF1) RefSeq Summary (NM_001242789): This gene encodes one of the three subunits of the RNA polymerase III transcription factor complex. This complex plays a central role in transcription initiation by RNA polymerase III on genes encoding tRNA, 5S rRNA, and other small structural RNAs. The gene product belongs to the TF2B family. Several alternatively spliced variants encoding different isoforms, that function at different promoters transcribed by RNA polymerase III, have been identified. [provided by RefSeq, Jun 2011]. Gencode Transcript: ENST00000635152.1 Gencode Gene: ENSG00000185024.18 Transcript (Including UTRs) Position: hg38 chr14:105,209,289-105,222,545 Size: 13,257 Total Exon Count: 8 Strand: -
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse
Rat
Zebrafish
D. melanogaster
C. elegans
S. cerevisiae
No ortholog
No ortholog
No ortholog
No ortholog
No ortholog
No ortholog
Descriptions from all associated GenBank mRNAs
LF385530 - JP 2014500723-A/193033: Polycomb-Associated Non-Coding RNAs. MA621107 - JP 2018138019-A/193033: Polycomb-Associated Non-Coding RNAs. U28838 - Human transcription factor TFIIIB 90 kDa subunit (hTFIIIB90) mRNA, complete cds. BC086856 - Homo sapiens BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae), mRNA (cDNA clone MGC:105048 IMAGE:6166751), complete cds. U75276 - Human TFIIB related factor hBRF (HBRF) mRNA, complete cds. AK295579 - Homo sapiens cDNA FLJ58798 complete cds, highly similar to Transcription factor IIIB 90 kDa subunit. AK294899 - Homo sapiens cDNA FLJ58760 complete cds, highly similar to Transcription factor IIIB 90 kDa subunit. AB527272 - Synthetic construct DNA, clone: pF1KB3029, Homo sapiens BRF1 gene for BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB, without stop codon, in Flexi system. BC071637 - Homo sapiens BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae), mRNA (cDNA clone IMAGE:4177747), partial cds. AK126499 - Homo sapiens cDNA FLJ44535 fis, clone UTERU3004709. AK125024 - Homo sapiens cDNA FLJ43034 fis, clone BRTHA3001721, highly similar to Homo sapiens BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae) (BRF1). AK124665 - Homo sapiens cDNA FLJ42674 fis, clone BRAMY2029988, highly similar to Transcription factor IIIB 90 kDa subunit. AJ297407 - Homo sapiens mRNA for transcription factor II B-related factor, isoform 3 (BRF gene). AJ297406 - Homo sapiens mRNA for transcription factor II B-related factor, isoform 2 (BRF gene). AK096471 - Homo sapiens cDNA FLJ39152 fis, clone OCBBF2001910, highly similar to Transcription factor IIIB 90 kDa subunit. JD515662 - Sequence 496686 from Patent EP1572962. BC103859 - Homo sapiens BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae), mRNA (cDNA clone IMAGE:40003193), complete cds. BC103860 - Homo sapiens BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae), mRNA (cDNA clone IMAGE:40003197), complete cds. BC103861 - Homo sapiens BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae), mRNA (cDNA clone IMAGE:40003203), complete cds. BC133655 - Homo sapiens BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae), mRNA (cDNA clone IMAGE:40003194), complete cds. JD367418 - Sequence 348442 from Patent EP1572962. JD247512 - Sequence 228536 from Patent EP1572962. JD474345 - Sequence 455369 from Patent EP1572962. JD429505 - Sequence 410529 from Patent EP1572962. JD137312 - Sequence 118336 from Patent EP1572962. JD376424 - Sequence 357448 from Patent EP1572962. JD129323 - Sequence 110347 from Patent EP1572962. JD382238 - Sequence 363262 from Patent EP1572962. JD103051 - Sequence 84075 from Patent EP1572962. JD121749 - Sequence 102773 from Patent EP1572962. JD226818 - Sequence 207842 from Patent EP1572962. JD370555 - Sequence 351579 from Patent EP1572962. JD407215 - Sequence 388239 from Patent EP1572962. JD228371 - Sequence 209395 from Patent EP1572962. JD192970 - Sequence 173994 from Patent EP1572962. JD104421 - Sequence 85445 from Patent EP1572962. JD380845 - Sequence 361869 from Patent EP1572962. JD281843 - Sequence 262867 from Patent EP1572962. DQ581525 - Homo sapiens piRNA piR-49637, complete sequence. JD207972 - Sequence 188996 from Patent EP1572962. JD400892 - Sequence 381916 from Patent EP1572962.
Biochemical and Signaling Pathways
BioCarta from NCI Cancer Genome Anatomy Project h_RNApol3Pathway - RNA polymerase III transcription