Human Gene CEP20 (ENST00000255759.11) from GENCODE V44
Description: Homo sapiens centrosomal protein 20 (CEP20), transcript variant 8, non-coding RNA. (from RefSeq NR_130756)
Gencode Transcript: ENST00000255759.11
Gencode Gene: ENSG00000133393.13
Transcript (Including UTRs)
Position: hg38 chr16:15,865,719-15,888,603 Size: 22,885 Total Exon Count: 5 Strand: -
Coding Region
Position: hg38 chr16:15,867,440-15,888,585 Size: 21,146 Coding Exon Count: 5
Data last updated at UCSC: 2023-08-18 00:09:47
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: FOPNL_HUMAN
DESCRIPTION: RecName: Full=LisH domain-containing protein FOPNL; AltName: Full=FGFR1OP N-terminal-like protein; AltName: Full=FOP-related protein of 20 kDa;
FUNCTION: Involved in the biogenesis of cilia.SUBUNIT: Homooligomer; probably required for localization to centrosomes.SUBCELLULAR LOCATION: Cell projection, cilium (By similarity). Cytoplasm, cytoskeleton, cilium basal body (By similarity). Cytoplasm, cytoskeleton, centrosome. Cytoplasmic granule. Note=Localizes to pericentriolar satellites, small (70-100 nm) cytoplasmic granules associated with the centrosome.TISSUE SPECIFICITY: Widely expressed. Detected in brain, heart, kidney, liver, lung, skeletal muscle, placenta and intestine.SIMILARITY: Belongs to the FGFR1OP family.SIMILARITY: Contains 1 LisH domain.
Primer design for this transcript
RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR018993 - FOP_dimerisation-dom_N
IPR006594 - LisH_dimerisation
Pfam Domains: PF09398 - FOP N terminal dimerisation domain
ModBase Predicted Comparative 3D Structure on Q96NB1
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
AY507846 - Homo sapiens pluripotent embryonic stem cell-related protein (PHSECRG2) mRNA, complete cds.AL832498 - Homo sapiens mRNA; cDNA DKFZp686N1651 (from clone DKFZp686N1651).AK055715 - Homo sapiens cDNA FLJ31153 fis, clone IMR322001600.AK056798 - Homo sapiens cDNA FLJ32236 fis, clone PLACE6004931.JD207499 - Sequence 188523 from Patent EP1572962.JD162541 - Sequence 143565 from Patent EP1572962.JD315086 - Sequence 296110 from Patent EP1572962.JD466972 - Sequence 447996 from Patent EP1572962.JD545393 - Sequence 526417 from Patent EP1572962.BC022321 - Homo sapiens chromosome 16 open reading frame 63, mRNA (cDNA clone MGC:22646 IMAGE:4702249), complete cds.JD491272 - Sequence 472296 from Patent EP1572962.JD098137 - Sequence 79161 from Patent EP1572962.JD374409 - Sequence 355433 from Patent EP1572962.JD238895 - Sequence 219919 from Patent EP1572962.JD356651 - Sequence 337675 from Patent EP1572962.JD476673 - Sequence 457697 from Patent EP1572962.JD069703 - Sequence 50727 from Patent EP1572962.JD379490 - Sequence 360514 from Patent EP1572962.JD383761 - Sequence 364785 from Patent EP1572962.JD267717 - Sequence 248741 from Patent EP1572962.JD321649 - Sequence 302673 from Patent EP1572962.JD064552 - Sequence 45576 from Patent EP1572962.JD545500 - Sequence 526524 from Patent EP1572962.JD242854 - Sequence 223878 from Patent EP1572962.JD329825 - Sequence 310849 from Patent EP1572962.JD333271 - Sequence 314295 from Patent EP1572962.JD242853 - Sequence 223877 from Patent EP1572962.JD364147 - Sequence 345171 from Patent EP1572962.JD071849 - Sequence 52873 from Patent EP1572962.JD121107 - Sequence 102131 from Patent EP1572962.JD069894 - Sequence 50918 from Patent EP1572962.JD519019 - Sequence 500043 from Patent EP1572962.DQ584967 - Homo sapiens piRNA piR-52079, complete sequence.JD534095 - Sequence 515119 from Patent EP1572962.HQ447790 - Synthetic construct Homo sapiens clone IMAGE:100071131; CCSB013027_01 chromosome 16 open reading frame 63 (C16orf63) gene, encodes complete protein.KJ895382 - Synthetic construct Homo sapiens clone ccsbBroadEn_04776 FOPNL gene, encodes complete protein.
Other Names for This Gene
Alternate Gene Symbols: C16orf63, ENST00000255759.1, ENST00000255759.10, ENST00000255759.2, ENST00000255759.3, ENST00000255759.4, ENST00000255759.5, ENST00000255759.6, ENST00000255759.7, ENST00000255759.8, ENST00000255759.9, FOPNL, FOPNL_HUMAN, FOR20, NR_130756, PHSECRG2, Q96NB1, uc002dec.1, uc002dec.2, uc002dec.3UCSC ID: ENST00000255759.11RefSeq Accession: NM_144600
Protein: Q96NB1
(aka FOPNL_HUMAN)
CCDS: CCDS10567.1
Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.