ID:INCA1_HUMAN DESCRIPTION: RecName: Full=Protein INCA1; AltName: Full=Inhibitor of CDK interacting with cyclin A1; SUBUNIT: Interacts with CCNA1. Identified in a complex with CCNA1 and CDK2. SUBCELLULAR LOCATION: Nucleus. TISSUE SPECIFICITY: Detected in testis, and at lower levels in ovary. Detected at very low levels in testis tumors. PTM: Phosphorylated when part of a complex with CCNA1 and CDK2. Strongly phosphorylated by CDK2 on its C-terminal region spanning amino acid 149-221. Less intensively phosphorylated by CDK2 on its first 75 amino acid residues. SIMILARITY: Belongs to the INCA family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q0VD86
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
