Human Gene ABCC3 (ENST00000571855.1) from GENCODE V44
  Description: ATP binding cassette subfamily C member 3 (from HGNC ABCC3)
Gencode Transcript: ENST00000571855.1
Gencode Gene: ENSG00000108846.16
Transcript (Including UTRs)
   Position: hg38 chr17:50,663,160-50,664,721 Size: 1,562 Total Exon Count: 1 Strand: +


Page IndexSequence and LinksPrimersMalaCardsCTDRNA-Seq Expression
Microarray ExpressionOther SpeciesmRNA DescriptionsPathwaysOther NamesMethods
Data last updated at UCSC: 2023-08-18 00:09:47

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr17:50,663,160-50,664,721)mRNA (may differ from genome)No protein
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaEnsembl
ExonPrimerGencodeHGNCLynxMalacardsPubMed
Wikipedia

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  MalaCards Disease Associations
  MalaCards Gene Search: ABCC3
Diseases sorted by gene-association score: dubin-johnson syndrome (24), extrahepatic cholestasis (23), cholangiolocellular carcinoma (13), cholestasis (10), bile duct carcinoma (7), bile duct disease (5), biliary tract disease (4), hepatocellular carcinoma (2)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 90.11 RPKM in Adrenal Gland
Total median expression: 433.06 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  BC046126 - Homo sapiens ATP-binding cassette, sub-family C (CFTR/MRP), member 3, mRNA (cDNA clone IMAGE:5212832), partial cds.
AF009670 - Homo sapiens multidrug resistance-associated protein homolog MRP3 (MRP3) mRNA, complete cds.
Y17151 - Homo sapiens mRNA for multidrug resistance protein 3 (ABCC3).
BC058907 - Homo sapiens ATP-binding cassette, sub-family C (CFTR/MRP), member 3, mRNA (cDNA clone IMAGE:5214188).
AF085690 - Homo sapiens multidrug resistance-associated protein 3 (MRP3) mRNA, complete cds.
AF085691 - Homo sapiens multidrug resistance-associated protein 3A (MRP3) mRNA, complete cds.
AF085692 - Homo sapiens multidrug resistance-associated protein 3B (MRP3) mRNA, complete cds.
BC104952 - Homo sapiens ATP-binding cassette, sub-family C (CFTR/MRP), member 3, mRNA (cDNA clone IMAGE:8143955), partial cds.
BC137347 - Homo sapiens ATP-binding cassette, sub-family C (CFTR/MRP), member 3, mRNA (cDNA clone MGC:168968 IMAGE:9021345), complete cds.
BC137348 - Homo sapiens ATP-binding cassette, sub-family C (CFTR/MRP), member 3, mRNA (cDNA clone MGC:168969 IMAGE:9021346), complete cds.
AB208954 - Homo sapiens mRNA for ATP-binding cassette, sub-family C, member 3 isoform MRP3 variant protein.
AF083552 - Homo sapiens canalicular multispecific organic anion transporter 2 (CMOAT2) mRNA, complete cds.
AB010887 - Homo sapiens mRNA for multidrug resistance-associated protein(MRP)-like protein-2 (MLP-2), complete cds.
KJ892604 - Synthetic construct Homo sapiens clone ccsbBroadEn_01998 ABCC3 gene, encodes complete protein.
BC050370 - Homo sapiens ATP-binding cassette, sub-family C (CFTR/MRP), member 3, mRNA (cDNA clone IMAGE:5761266), partial cds.
AF104943 - Homo sapiens ABC transporter MOAT-D (MOAT-D) mRNA, complete cds.
AB384796 - Synthetic construct DNA, clone: pF1KB3349, Homo sapiens ABCC3 gene for ATP-binding cassette, sub-family C member 3, complete cds, without stop codon, in Flexi system.
BX649137 - Homo sapiens mRNA; cDNA DKFZp686E22157 (from clone DKFZp686E22157).
BC127655 - Homo sapiens chromobox homolog 2 (Pc class homolog, Drosophila), mRNA (cDNA clone IMAGE:40119320), with apparent retained intron.
BC131755 - Homo sapiens ninjurin 2, mRNA (cDNA clone IMAGE:40119218).

-  Biochemical and Signaling Pathways
  BioCarta from NCI Cancer Genome Anatomy Project
h_mrpPathway - Multi-Drug Resistance Factors
h_nuclearRsPathway - Nuclear Receptors in Lipid Metabolism and Toxicity

-  Other Names for This Gene
  Alternate Gene Symbols: BX649137, uc002ism.1, uc002ism.2, uc002ism.3, uc002ism.4
UCSC ID: ENST00000571855.1
Representative RNA: BX649137

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.