Human Gene ANKRD29 (ENST00000322980.13) from GENCODE V44
  Description: Homo sapiens ankyrin repeat domain 29 (ANKRD29), transcript variant 2, mRNA. (from RefSeq NM_001308238)
Gencode Transcript: ENST00000322980.13
Gencode Gene: ENSG00000154065.17
Transcript (Including UTRs)
   Position: hg38 chr18:23,600,460-23,662,815 Size: 62,356 Total Exon Count: 9 Strand: -
Coding Region
   Position: hg38 chr18:23,601,226-23,662,730 Size: 61,505 Coding Exon Count: 9 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther Names
Methods
Data last updated at UCSC: 2023-08-18 00:09:47

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr18:23,600,460-23,662,815)mRNA (may differ from genome)Protein (268 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGencodeGeneCards
HGNCHPRDLynxMalacardsMGIneXtProt
PubMedUniProtKBBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: ANR29_HUMAN
DESCRIPTION: RecName: Full=Ankyrin repeat domain-containing protein 29;
SIMILARITY: Contains 8 ANK repeats.
SEQUENCE CAUTION: Sequence=BAC85555.1; Type=Miscellaneous discrepancy; Note=Intron retention;

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 10.85 RPKM in Lung
Total median expression: 167.15 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -39.1085-0.460 Picture PostScript Text
3' UTR -169.40766-0.221 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR002110 - Ankyrin_rpt
IPR020683 - Ankyrin_rpt-contain_dom

Pfam Domains:
PF00023 - Ankyrin repeat
PF12796 - Ankyrin repeats (3 copies)

ModBase Predicted Comparative 3D Structure on Q8N6D5
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
MGIRGD    
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Descriptions from all associated GenBank mRNAs
  HQ447368 - Synthetic construct Homo sapiens clone IMAGE:100070689; CCSB001736_02 ankyrin repeat domain 29 (ANKRD29) gene, encodes complete protein.
KJ900253 - Synthetic construct Homo sapiens clone ccsbBroadEn_09647 ANKRD29 gene, encodes complete protein.
AK123197 - Homo sapiens cDNA FLJ41203 fis, clone BRACE3000071.
BC030622 - Homo sapiens ankyrin repeat domain 29, mRNA (cDNA clone MGC:33520 IMAGE:4818619), complete cds.
AK057782 - Homo sapiens cDNA FLJ25053 fis, clone CBL04266.
JD279878 - Sequence 260902 from Patent EP1572962.
JD435258 - Sequence 416282 from Patent EP1572962.
JD474223 - Sequence 455247 from Patent EP1572962.
JD345305 - Sequence 326329 from Patent EP1572962.
JD194204 - Sequence 175228 from Patent EP1572962.
JD147684 - Sequence 128708 from Patent EP1572962.
JD113971 - Sequence 94995 from Patent EP1572962.
AK313667 - Homo sapiens cDNA, FLJ94249, highly similar to Homo sapiens ankyrin repeat domain 29 (ANKRD29), mRNA.
CU688952 - Synthetic construct Homo sapiens gateway clone IMAGE:100018768 5' read ANKRD29 mRNA.
JD125546 - Sequence 106570 from Patent EP1572962.
JD458015 - Sequence 439039 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: ANR29_HUMAN, B2R972, ENST00000322980.1, ENST00000322980.10, ENST00000322980.11, ENST00000322980.12, ENST00000322980.2, ENST00000322980.3, ENST00000322980.4, ENST00000322980.5, ENST00000322980.6, ENST00000322980.7, ENST00000322980.8, ENST00000322980.9, NM_001308238, Q6ZWE8, Q8N6D5, Q96LU9, uc002kuo.1, uc002kuo.2, uc002kuo.3, uc002kuo.4
UCSC ID: ENST00000322980.13
RefSeq Accession: NM_001308238
Protein: Q8N6D5 (aka ANR29_HUMAN)
CCDS: CCDS77164.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.