Human Gene HSD11B1L (ENST00000581893.5) from GENCODE V44
Description: Homo sapiens hydroxysteroid 11-beta dehydrogenase 1 like (HSD11B1L), transcript variant d, mRNA. (from RefSeq NM_198708) RefSeq Summary (NM_001267869): This gene is a member of the hydroxysteroid dehydrogenase family. The encoded protein is similar to an enzyme that catalyzes the interconversion of inactive to active glucocorticoids (e.g. cortisone). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2012]. Gencode Transcript: ENST00000581893.5 Gencode Gene: ENSG00000167733.14 Transcript (Including UTRs) Position: hg38 chr19:5,681,009-5,688,522 Size: 7,514 Total Exon Count: 6 Strand: + Coding Region Position: hg38 chr19:5,686,986-5,687,945 Size: 960 Coding Exon Count: 4
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q7Z5J1
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.