Human Gene ZNF525 (ENST00000475179.5) from GENCODE V44
  Description: Homo sapiens zinc finger protein 525 (ZNF525), transcript variant 5, non-coding RNA. (from RefSeq NR_145447)
Gencode Transcript: ENST00000475179.5
Gencode Gene: ENSG00000203326.12
Transcript (Including UTRs)
   Position: hg38 chr19:53,365,713-53,386,581 Size: 20,869 Total Exon Count: 4 Strand: +
Coding Region
   Position: hg38 chr19:53,372,282-53,384,980 Size: 12,699 Coding Exon Count: 3 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA Descriptions
Other NamesMethods
Data last updated at UCSC: 2023-08-18 00:09:47

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr19:53,365,713-53,386,581)mRNA (may differ from genome)Protein (50 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGencodeGeneCards
HGNCLynxMGIPubMedUniProtKBBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: E7ENB8_HUMAN
DESCRIPTION: SubName: Full=Zinc finger protein 525;
CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 4.76 RPKM in Testis
Total median expression: 67.38 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -26.60114-0.233 Picture PostScript Text
3' UTR -424.501601-0.265 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR026613 - KRAB_dom_C2H2_Znf_fam
IPR001909 - Krueppel-associated_box

Pfam Domains:
PF01352 - KRAB box

ModBase Predicted Comparative 3D Structure on E7ENB8
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
MGI     
Protein Sequence     
Alignment     

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0003676 nucleic acid binding

Biological Process:
GO:0006355 regulation of transcription, DNA-templated

Cellular Component:
GO:0005622 intracellular


-  Descriptions from all associated GenBank mRNAs
  AK293890 - Homo sapiens cDNA FLJ50389 complete cds, moderately similar to Zinc finger protein 611.
AK097037 - Homo sapiens cDNA FLJ39718 fis, clone SMINT2013695.
KJ904945 - Synthetic construct Homo sapiens clone ccsbBroadEn_14339 ZNF765-like gene, encodes complete protein.
AB075859 - Homo sapiens mRNA for KIAA1979 protein.
JD410784 - Sequence 391808 from Patent EP1572962.
JD550098 - Sequence 531122 from Patent EP1572962.
JD550097 - Sequence 531121 from Patent EP1572962.
JD449410 - Sequence 430434 from Patent EP1572962.
JD553129 - Sequence 534153 from Patent EP1572962.
JD515187 - Sequence 496211 from Patent EP1572962.
JD238277 - Sequence 219301 from Patent EP1572962.
JD299811 - Sequence 280835 from Patent EP1572962.
JD287701 - Sequence 268725 from Patent EP1572962.
JD266020 - Sequence 247044 from Patent EP1572962.
JD441298 - Sequence 422322 from Patent EP1572962.
JD088216 - Sequence 69240 from Patent EP1572962.
JD532314 - Sequence 513338 from Patent EP1572962.
JD443086 - Sequence 424110 from Patent EP1572962.
JD078457 - Sequence 59481 from Patent EP1572962.
JD286731 - Sequence 267755 from Patent EP1572962.
JD510914 - Sequence 491938 from Patent EP1572962.
JD088614 - Sequence 69638 from Patent EP1572962.
JD267391 - Sequence 248415 from Patent EP1572962.
JD447656 - Sequence 428680 from Patent EP1572962.
JD085085 - Sequence 66109 from Patent EP1572962.
JD249534 - Sequence 230558 from Patent EP1572962.
JD377976 - Sequence 359000 from Patent EP1572962.
JD354006 - Sequence 335030 from Patent EP1572962.
JD269551 - Sequence 250575 from Patent EP1572962.
JD517053 - Sequence 498077 from Patent EP1572962.
JD544934 - Sequence 525958 from Patent EP1572962.
JD242123 - Sequence 223147 from Patent EP1572962.
JD563394 - Sequence 544418 from Patent EP1572962.
JD551636 - Sequence 532660 from Patent EP1572962.
JD507271 - Sequence 488295 from Patent EP1572962.
JD427335 - Sequence 408359 from Patent EP1572962.
JD279448 - Sequence 260472 from Patent EP1572962.
JD488813 - Sequence 469837 from Patent EP1572962.
JD376849 - Sequence 357873 from Patent EP1572962.
JD376848 - Sequence 357872 from Patent EP1572962.
JD417931 - Sequence 398955 from Patent EP1572962.
JD523990 - Sequence 505014 from Patent EP1572962.
JD146402 - Sequence 127426 from Patent EP1572962.
JD083185 - Sequence 64209 from Patent EP1572962.
JD414269 - Sequence 395293 from Patent EP1572962.
JD060500 - Sequence 41524 from Patent EP1572962.
JD396765 - Sequence 377789 from Patent EP1572962.
JD112273 - Sequence 93297 from Patent EP1572962.
JD112274 - Sequence 93298 from Patent EP1572962.
JD089470 - Sequence 70494 from Patent EP1572962.
JD275493 - Sequence 256517 from Patent EP1572962.
JD275494 - Sequence 256518 from Patent EP1572962.
JD275495 - Sequence 256519 from Patent EP1572962.
JD353366 - Sequence 334390 from Patent EP1572962.
JD259894 - Sequence 240918 from Patent EP1572962.
JD261669 - Sequence 242693 from Patent EP1572962.
JD430209 - Sequence 411233 from Patent EP1572962.
JD557389 - Sequence 538413 from Patent EP1572962.
JD529240 - Sequence 510264 from Patent EP1572962.
JD169373 - Sequence 150397 from Patent EP1572962.
JD041391 - Sequence 22415 from Patent EP1572962.
JD041392 - Sequence 22416 from Patent EP1572962.
JD321135 - Sequence 302159 from Patent EP1572962.
JD388358 - Sequence 369382 from Patent EP1572962.
JD118451 - Sequence 99475 from Patent EP1572962.
JD531710 - Sequence 512734 from Patent EP1572962.
JD208286 - Sequence 189310 from Patent EP1572962.
JD282449 - Sequence 263473 from Patent EP1572962.
JD429940 - Sequence 410964 from Patent EP1572962.
JD556753 - Sequence 537777 from Patent EP1572962.
JD091293 - Sequence 72317 from Patent EP1572962.
JD092618 - Sequence 73642 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: E7ENB8, E7ENB8_HUMAN, ENST00000475179.1, ENST00000475179.2, ENST00000475179.3, ENST00000475179.4, NR_145447, uc002qbl.1, uc002qbl.2, uc002qbl.3
UCSC ID: ENST00000475179.5
RefSeq Accession: NR_145447
Protein: E7ENB8

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.