Human Gene NOL10 (ENST00000345985.7) from GENCODE V44
Description: Homo sapiens nucleolar protein 10 (NOL10), transcript variant 3, mRNA. (from RefSeq NM_001261394)
Gencode Transcript: ENST00000345985.7
Gencode Gene: ENSG00000115761.17
Transcript (Including UTRs)
Position: hg38 chr2:10,570,766-10,689,972 Size: 119,207 Total Exon Count: 20 Strand: -
Coding Region
Position: hg38 chr2:10,572,071-10,689,861 Size: 117,791 Coding Exon Count: 20
Data last updated at UCSC: 2023-08-18 00:09:47
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: NOL10_HUMAN
DESCRIPTION: RecName: Full=Nucleolar protein 10;
SUBCELLULAR LOCATION: Nucleus, nucleolus.SIMILARITY: Belongs to the WD repeat NOL10/ENP2 family.SIMILARITY: Contains 5 WD repeats.
Primer design for this transcript
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
Press "+" in the title bar above to open this section.
mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR012580 - NUC153
IPR015943 - WD40/YVTN_repeat-like_dom
IPR001680 - WD40_repeat
IPR017986 - WD40_repeat_dom
Pfam Domains: PF08159 - NUC153 domain
ModBase Predicted Comparative 3D Structure on Q9BSC4
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
AK024137 - Homo sapiens cDNA FLJ14075 fis, clone HEMBB1001905, weakly similar to TRICHOHYALIN.BC005125 - Homo sapiens nucleolar protein 10, mRNA (cDNA clone MGC:10515 IMAGE:3841643), complete cds.AK299617 - Homo sapiens cDNA FLJ53179 complete cds, highly similar to Nucleolar protein 10.AK297169 - Homo sapiens cDNA FLJ54700 complete cds, highly similar to Nucleolar protein 10.AK290680 - Homo sapiens cDNA FLJ76267 complete cds, highly similar to Homo sapiens nucleolar protein 10, mRNA.KJ894756 - Synthetic construct Homo sapiens clone ccsbBroadEn_04150 NOL10 gene, encodes complete protein.JD379577 - Sequence 360601 from Patent EP1572962.JD493916 - Sequence 474940 from Patent EP1572962.JD062997 - Sequence 44021 from Patent EP1572962.JD332531 - Sequence 313555 from Patent EP1572962.JD319080 - Sequence 300104 from Patent EP1572962.JD382567 - Sequence 363591 from Patent EP1572962.JD507433 - Sequence 488457 from Patent EP1572962.JD197213 - Sequence 178237 from Patent EP1572962.JD334630 - Sequence 315654 from Patent EP1572962.JD428179 - Sequence 409203 from Patent EP1572962.JD081952 - Sequence 62976 from Patent EP1572962.JD281140 - Sequence 262164 from Patent EP1572962.JD323190 - Sequence 304214 from Patent EP1572962.JD299412 - Sequence 280436 from Patent EP1572962.JD559245 - Sequence 540269 from Patent EP1572962.JD234370 - Sequence 215394 from Patent EP1572962.JD283167 - Sequence 264191 from Patent EP1572962.AK024000 - Homo sapiens cDNA FLJ13938 fis, clone Y79AA1000824.CU675005 - Synthetic construct Homo sapiens gateway clone IMAGE:100017772 5' read NOL10 mRNA.BC037841 - Homo sapiens nucleolar protein 10, mRNA (cDNA clone IMAGE:4814644).JD462597 - Sequence 443621 from Patent EP1572962.JD538161 - Sequence 519185 from Patent EP1572962.JD550688 - Sequence 531712 from Patent EP1572962.JD256388 - Sequence 237412 from Patent EP1572962.
Other Names for This Gene
Alternate Gene Symbols: A8K3R5, ENST00000345985.1, ENST00000345985.2, ENST00000345985.3, ENST00000345985.4, ENST00000345985.5, ENST00000345985.6, NM_001261394, NOL10_HUMAN, Q53RC9, Q96TA5, Q9BSC4, Q9H7Y7, Q9H855, uc002rap.1, uc002rap.2, uc002rap.3, uc002rap.4UCSC ID: ENST00000345985.7RefSeq Accession: NM_001261394
Protein: Q9BSC4
(aka NOL10_HUMAN)
CCDS: CCDS58698.1
Methods, Credits, and Use Restrictions
Click here
for details on how this gene model was made and data restrictions if any.